bradykinesia


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Related to bradykinesia: dyskinesia

bradykinesia

[‚brā·dē·kə′nēzh·yə]
(medicine)
Extreme slowness in movement.
References in periodicals archive ?
However, when major loss of dopaminergic neuron function occurs in PD, more and more impulses are facilitated, leading to the four cardinal symptoms of PD: tremor, bradykinesia, rigidity, and postural instability (Jankovic, 2008).
Table 19: Incidence of EPS Compared to Placebo in the Adjunctive Therapy Bipolar Depression Studies Adverse Event Term Placebo LATUDA 20 to (N=334) 120 mg/day (%) (N=360)(%) All EPS events 13 24 Ail EPS events, 9 14 excluding Akathisia/Restlessness Akathisia 5 11 Dystonia* 1 1 Parkinsonism** 8 13 Restlessness 1 4 Note: Figures rounded to the nearest integer *Dystonia includes adverse event terms: dystonia, oculogyric crisis, oromandibular dystonia, tongue spasm, torticollis, and trismus **Parkinsonism includes adverse event terms: bradykinesia, cogwheel rigidity, drooling, extrapyramidal disorder, glabellar reflex abnormal, hypokinesia, muscle rigidity, parkinsonism, psychomotor retardation, and tremor
However levodopa and peripheral decarboxylase inhibitor, carbedopa, remain the standard of treatments for Parkinsonism with bradykinesia and rigidity.
Parkinson's disease (PD), a neurodegenerative disorder, is characterized by the selective degeneration of the nigrostriatal dopaminergic neurons, continuing or permanent deficiency of dopamine, accretion of an abnormal form of alpha synuclein in the adjacent neurons, and dysregulation of ubiquitin proteasomal system, mitochondrial metabolism, permeability and integrity, and cellular apoptosis resulting in rigidity, bradykinesia, resting tremor, and postural instability.
The three most telling symptoms of such a condition are tremors, a slowness of movement known as Bradykinesia, and rigidity or stiffness.
The neurodegenerative death of dopaminergic neurons in the pars compacta of the substantia nigra leads to the classic triad of rigidity, resting tremor and bradykinesia (2).
The major motor symptoms are rest tremor, rigidity, bradykinesia, akinesia, and postural instability.
22) This develops over time as a result of bradykinesia (slowness of movement), loss of postural reflexes, and rigidity (increased tone).
To address the possibility that parkinsonian bradykinesia was exacerbated by the presence of an obstacle, we conducted a post hoc analysis of CVCOM using data obtained from no music trials of unobstructed (no obstacle) and obstructed (obstacle) walking trials.
In the graphical deficits due to motor difficulties it can be found the presence of diseases such as Parkinson's Disease (PD) (Lange, 2006; Tucha, 2006; Longstaff, 2003); PD symptoms include bradykinesia, tremor, rigidity, reduced manual ability and loss of accuracy, which cause typical phenomena that can be classified using graphic gesture analysis and then related to the specific pathology (Tucha, 2006).
Yes/No Bradykinesia Are you taking longer to do (overall slowing) things (dressing, eating or at work) than your family at members or work colleagues would take?
Bradykinesia is examined by observation and objectively by measuring the time required to complete a task.