The new approach, which was included by Congress as part of the 21st Century Cures Act, allows the FDA to simultaneously update the breakpoints
for multiple drugs that have the same active ingredient and share that information transparently via a dedicated FDA web page that will list FDA-recognized breakpoints
And so, once again, we're asking you to join thousands of others in what has now become an annual effort here at Breakpoint
and the Colson Center: The 21 Days of Prayer for Life.
The control information leads the target processor into debugging mode such as single-stepping, breakpoint
of SFR, breakpoint
of address, etc.
Applying the CLSI susceptibility breakpoint
of 2 [micro]g/mL for moxifloxacin, only 6% of the strains would be considered susceptible.
Cohen's kappa coefficient was used to assess the correlation between the ODD and both the penicillin MIC, using CLSI meningeal breakpoints
, and the ceftriaxone MIC, using CLSI meningeal and non-meningeal breakpoints
1, A and B, correspond to translocations with breakpoint
positions of m = 10,40, 70, and 120, respectively, for X = 140 bp where both ends are selected to be unique.
Thus we define the feature of tangent angle as the angle between the extension direction of one breakpoint
and the vector from it to another possible matching breakpoint
Use of non-meningitis breakpoints
in this study demonstrates no penicillin resistance.
Antimicrobial susceptibility breakpoints
are established based on 1) the pharmacokinetic and pharmacodynamic properties of an antimicrobial agent and 2) data correlating individual MIC results with patient outcomes.
The point is that an outside collection agency takes the situation to the next psychological breakpoint
In an epilogue, Clarke discusses how close the technology in Breakpoint
is to reality.
Key points can play an instrumental role in the evolution of matches as they are mechanisms by which momentum can shift back and forth between players and one of the more obvious examples of a key-point situation is when a player holds or is facing, a breakpoint