lobule

(redirected from breast lobule)
Also found in: Dictionary, Thesaurus, Medical.

lobule

[′läb·yül]
(biology)
A small lobe.
A division of a lobe.
References in periodicals archive ?
Women are born with a small number of Type 1 breast lobules, which are units of milk glands and duct cells.
Morphologic features of the lung tumor (A through C); with TTF-1 staining (D); with ER staining at low power (E) and high power (F); and with napsin A staining of the tumor (G) and in residual, benign breast lobules (H) (hematoxylin-eosin, original magnifications 320 [A], x40 [B], and x100 [C]; original magnification x40 [D]; original magnifications x40 [E] and x100 [F]; original magnification x100 [G and H]).
Pathologically, inflammation affecting breast lobules or lobulitis and the formation of non-caseating granulomas composed of clustered epitheloid histiocytes is present.
The study shows that acini (AS-ih-nye), the small milk-producing elements in breast lobules, can be counted in sample biopsies.
Spiculations and pectoralis muscle/fascial involvement may not be apparent intraoperatively because the lesion may appear to be pushing on existing breast lobules without destroying or infiltrating tissue.
Interestingly, CCCTCbinding factor (CTCF) and Dipeptidase 1 (DPEP1), both candidate tumor-suppressor genes, were found to have decreased expression in LCIS versus normal breast lobules.