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osteogenesis imperfecta |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.04 sec. |
osteogenesis imperfectaGroup of connective-tissue diseases in which the bones are very fragile. Several forms probably reflect different degrees of expression of the same disorder. Persons with osteogenesis imperfecta type I are normal at birth, but fractures occur easily; in van der Hoeve syndrome the sclerae are bluish, bone deformities in the skull cause deafness, double-jointedness occurs, and skin is abnormally thin. Babies with osteogenesis imperfecta type II, if not stillborn, are born with fractures, and fractures continue to occur, causing severe crippling; survival to adulthood is rare. osteogenesis imperfecta [¦äs·tē·ō′jen·ə·səs ‚im·pər′fek·tə] (medicine) A disease inherited as an autosomal dominant and characterized by hypoplasia of osteoid tissue and collagen, resulting in bone fractures. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Chronic hyperphosphatemia is associated with serious health risks including renal osteodystrophy (resulting in bone pain, brittle bones, skeletal deformities and fractures), and heart failure caused by cardiovascular calcification. Too many crunches and obsessive dieting can lead to brittle bones and misaligned spinal cords. Dancers with nutritional deficiencies associated with dieting may offset common problems, such as brittle bones, by seeing a registered dietician. |
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