bronchodilation


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bronchodilation

[¦bräŋ·kō‚dī′lā·shən]
(physiology)
Widening of the air passages in bronchi and bronchioles.
References in periodicals archive ?
Beta-2 receptor activation inhibits contraction of smooth muscle, leading to bronchodilation and decreased resistance to airflow.
In conclusion, the results of this pilot study suggest that thoracic gas compression volume was not changed significantly after the administration of long-acting bronchodilators, even if both study drugs elicited significant bronchodilation in spirometric measurements.
Aclidinium bromide is an anticholinergic or long-acting muscarinic antagonist (LAMA) that produces bronchodilation by inhibiting the muscarinic M3 receptor in the airway smooth muscle.
The data demonstrates that, as designed, the new commercially scalable, suspension formulation is well tolerated and has allowed us to extend the dose range and the duration of bronchodilation effect that can be produced in COPD patients.
Methylxanthines, which are phosphodiesterase inhibitors, promote bronchodilation.
Tudorza produces bronchodilation by inhibiting acetylcholine's effect on muscarinic receptors in the airway smooth muscle.
As reported on 23 March 2015 and 8 June 2015, Phase 1b results in SAD and MAD studies of nebulised RPL554 with this new formulation in healthy volunteers, have demonstrated that the drug is well tolerated in doses up to 16 times larger than those previously demonstrated to produce bronchodilation using the prior formulation.
We need to provide the maximum bronchodilation as possible.
Boehringer Ingelheim has designed StriverdiA RespimatA as a possible future combination partner for SpirivaA to provide additional bronchodilation in the maintenance treatment of COPD," Professor Dugi continued.
1] and FVC before and after bronchodilation showed significant improvements that were maintained at all time points after randomization.
An alternative explanation of bronchodilation is that theophylline acts by blocking the action of adenosine.
The primary objective here is to further confirm the safety and tolerability seen in earlier parts of the trial, as well as to investigate bronchodilation in these COPD patients.