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busulfan

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busulfan [‚byü′səl·fən]
(pharmacology)
CH3SO2O(CH2)4OSO2CH3Crystals with a melting point of 114-118°C; soluble in acetone at 25°C; used as an antineoplastic drug.


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1/2] of busulfan (y) Biliary excretion Serum protein Adult level (aa) Serum cholinesterase Serum arylesterase Alcohol 91 % - in vitro EA (ee) dehydrogenase Abbreviations: APAP, acetaminophen; BSP, bromosulfophthalein; CBZ, carbamazepine; CBZ-E, carbamazepine-epoxide; DMO, dimethadione; EA, enzyme activity; EH, epoxide hydrolase; GFR, glomerular filtration rate; PL, protein level; TMO, trimethadione.
Incorporating children's toxicokinetics into a risk framework by Sonawane, Babasaheb / Environmental Health Perspectives
In the study's earlier years, the first 12 children with sickle-cell disease received a bone marrow transplant plus busulfan and cyclophosphamide, two drugs known to facilitate transplants.
Researchers target sickle-cell cure. (Biomedicine) by Science News
The conditioning regimen for the transplant consisted of busulfan, cyclophosphamid, and antithymocyte globulin administered with a Hickman catheter.
Candida dubliniensis Candidemia in Patients with Chemotherapy-Induced ... by Verweij, Paul E. / Emerging Infectious Diseases
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