busulfan


Also found in: Dictionary, Medical, Financial, Wikipedia.

busulfan

[‚byü′səl·fən]
(pharmacology)
CH3SO2O(CH2)4OSO2CH3 Crystals with a melting point of 114-118°C; soluble in acetone at 25°C; used as an antineoplastic drug.
References in periodicals archive ?
For the 12 months ending 30 September 2017, the US sales for Busulfan Injection, 60 mg/10 ml (6 mg/ml) single-dose vial were approximately USD97m, according to IQVIA.
Accelerated ovarian aging in mice by treatment of busulfan and cyclophosphamide.
Slight decrease in Kitlg mRNA expression has also been observed in mice treated with busulfan, albeit this reduction was not statistically significant In contrast with GDNF and FGF2, KITLG is believed to be involved in SSCs differentiation.
Las interacciones farmacocineticas de los AD son poco probables con busulfan, clorambucil, melfalan, tioguanina, cisplatino, carboplatino, oxaliplatino, mercaptopurina, 5-fluorouracilo, estramustina, daunorubicin, temozolomida, mecloretamina, doxorubicina, epirubicina, vorinostat.
3) These include the antiarrhythmic drug amiodarone, the chemotherapeutic agents bleomycin, busulfan, carmustine and cyclophosphamide, the immunosuppressive drugs sirolimus and everolimus and many others.
A decision was made to proceed with SCT from a matched unrelated donor using reduced intensity conditioning (RIC): fludarabine 30 mg/m for 4 days and busulfan 3.
Others (cyclophosphamide, busulfan, and carmustine) can cause it even years after completion of therapy.
busulfan, melphalan, cyclophosphamide) doxorubicin, daunorubicin cause stomatitis and patients with hematological malignancies are more prone to the occurrence of oral complications [7].
busulfan monitoring in bone marrow transplantation), a few calibration measurements that could be collected at random instead of the current strict timing required for current TDM would be a welcome change.
It is estimated that this type of complication after allo-HSCT was observed in 0-70% of cases, and the risk of these adverse events increases in the group of patients with liver damage, in which myeloablative chemotherapy or busulfan therapy was used [25].
Busulipo has been developed by Pharmalink as a liposome/lipid complex formulation that improves the safety and stability of the chemotherapy agent busulfan, and is aimed at becoming the new gold standard for use in conditioning prior to HSCT.
J'etais incertaine de la portee [benefique] du Busulfan, mais je voulais tenter quelque chose qui pourrait s'averer le miracle inattendu et l'oncologue [de l'enfant] voulait vraiment le tenter.