butyrolactone


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butyrolactone

[¦byüd·ə·rō′lak‚tōn]
(organic chemistry)
C4H6O2 A liquid, the anhydride of butyric acid; used as a solvent in the manufacture of plastics.
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FDA Warns Consumers About Products Containing Gamma Butyrolactone or GBL and Asks Companies to Issue a Recall (FDA Talk Paper, January 21, 1999)
The drug Gamma Hydroxybutyrate (GHB) which is broken down in the body into Gamma Butyrolactone can induce symptoms including euphoria, confusion and unconsciousness.
Mr Llwyd said: "In August, the Advisory Council on the Misuse of Drugs recommended that gamma butyrolactone, or GBL for short, becomes a Class C substance.
Tests later revealed she had Gamma Butyrolactone, known as GHB ( a drug capable of affecting the central nervous system ( in her blood.
Wright, 36, of Eastgarth, Newbiggin Hall, Newcastle, denies intentionally administering a substance, which the body transforms into Gamma Butyrolactone, to the woman, knowing she did not consent and with the intention of stupefying or overpowering her so as to enable himself or another to engage in sexual activity involving her.
END-USE APPLICATIONS/INDUSTRY II-31Applications of Succinic Acid Derivatives II-31Chemicals II-32Butanediol II-32Gamma Butyrolactone II-32Tetrahydrofuran II-32Polybutylenesuccinate II-32Pyrrolidones II-33Food Products II-33Pharmaceuticals II-33End-Uses of Bio-Based Succinic Acid II-33Applications of Bio-Succinic Acid II-34End-Use Applications & Industries of Succinic Acid andSuccinic Anhydride II-35
Anti-proliferative and a poptotic effects of butyrolactone lignans from Arctium lappa on leukemic cells.
It is thought they had swallowed a chemical, possibly gamma butyrolactone - known as GBL.
Forensic tests showed the drug in her system was Gamma Butyrolactone ( the breakdown of another drug GHB ( which depresses the central nervous system and can cause euphoria, confusion and unconsciousness and is used as an anaesthetic and as a hypnotic drug.
Out of the tested compounds, three benzophenanthridine alkaloids (1, 4, and 7), a dibenzyl butyrolactone lignan (10), and two 2-arylbenzofuran neolignans (12 and 13) displayed significant cytotoxicity to HCT116 cells, confirmed by the Guava Via-Count viability assay.
The major application segments for tetrahydrofuran, polybutylene terphthalate, gamma butyrolactone, polyurethane and others; whereas tetrahydrofuran constitutes the major application segment.
Gamma Hydroxybutyrate (GHB) and Gamma Butyrolactone (GBL), on the other hand, generally arrive from sources in Western Europe.