Cachexia

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cachexia

[ka′kek·sē·ə]
(medicine)
Weight loss, weakness, and wasting of the body encountered in certain diseases or in terminal illnesses.

Cachexia

 

a state of profound wasting and physical debility manifested by severe emaciation, weight loss, dry and flabby skin, loss of hair, disappearance of subcutaneous fat, atrophy of muscles and viscera, and low serum protein level. Edema, hemorrhages, and sometimes mental derangement can occur with cachexia. It results from prolonged malnutrition or starvation, severe metabolic disorders, chronic arsenic, lead, mercury, or fluorine poisoning, and severe lesions of the digestive tract (atrophy of the intestinal mucosa, condition after resection of the stomach and intestines). Cachexia may occur in severe cases of tuberculosis or other chronic infections, some lesions of the endocrine glands, (hypophysis, thyroid, adrenals, pancreas), large slow-healing wounds, abscesses, and malignant tumors (especially of the esophagus and stomach).

References in periodicals archive ?
MOSES, AW; SLATER, C; PRESTON, T; BARBER, MD & FEARON, KC 2004: Reduced total energy expenditure and physical activity in cachectic patients with pancreatic cancer can be modulated by an energy and protein dense oral supplement enriched with [omega]-3 fatty acids.
Serious adverse reactions may occur with MorphaBond which include addiction, abuse, and misuse, life-threatening respiratory depression especially in elderly, cachectic, and debilitated patients.
A 56-year-old cachectic woman with longstanding dysphagia and multiple episodes of aspiration pneumonia presented with orthostasis in the setting of poor oral intake, weight loss, and progressive failure to thrive.
On examination she was apyrexial and looked cachectic.
Dietary supplementation with a specific combination of high protein, leucine, and fish oil improves muscle function and daily activity in tumour-bearing cachectic mice.
The animal weighed 214 g and was severely cachectic.
Effect of a cancer cachectic factor on protein synthesis/degradation in murine C2C12 myoblasts: Modulation by elcosapentaenoric acid.
Effect of fish oil supplementation and physical activity on metabolism of normal and cachectic subjects.
5[degrees]C), and cachectic, with a 5 cm fluctuant mass with a visible point.
Cytokines, the acute-phase response, and resting energy expenditure in cachectic patients with pancreatic cancer.
Kiel explained that hard-shell pads that divert energy have a potential drawback in thin, cachectic patients, because the pads may not clear the trochanter, thus exerting force on the hip.