calcitonin


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calcitonin

[kal·sə′tō·nən]
(biochemistry)
A polypeptide, calcium-regulating hormone produced by the ultimobranchial bodies in vertebrates. Also known as thyrocalcitonin.
References in periodicals archive ?
The ORACAL study was a Phase 3 multinational, randomized, double-blind, double-dummy, placebo-controlled trial of OSTORA[TM] compared to placebo and to commercially available, synthetic salmon calcitonin administered by nasal spray.
However, with the application of a 10 ng/L threshold for pentagastrin testing as described above, the LOQ of 12 ng/L meant that patients with calcitonin concentrations between 9 and 12 ng/L (2% ofwomenand10% of men, in our experience) would potentially be missed with assays performed using the Liason reagent set.
The patient was treated with 100 IU of salmon calcitonin (Miacalcic[R], Novartis), diluted in 100 ml of normal saline, infused intravenously over one hour on three consecutive days.
In the calcitonin group, trabecular microarchitecture in the lower trochanter was preserved, according to T2-MRI findings, regardless of whether patients lost or gained total hip BMD.
There is no cross-reactivity with procalcitonin and calcitonin from other species (pig, salmon, chicken) at concentrations <40 mg/L.
During the first year of the study, the subjects were randomly assigned to receive either 10 mg of oral alendronate, 200 IU of calcitonin nasal spray, or an oral placebo every day.
8), who used HPLC-extracted calcitonin precursors from pooled serum of healthy males.
However, immunohistochemical staining of the sample for calcitonin yielded positive results.
Treatment with either estrogen, bisphosphonates, or calcitonin has been shown to increase bone mineral density and decrease the incidence of future fracture (J.
There was no cross-reaction with the synthetic SCT fragments 1-11 and 10-32 or with human synthetic calcitonin (Peninsula, Belmont, CA) up to a concentration of 9.
SAN DIEGO -- One year of treatment with alendronate was significantly more effective than calcitonin in restoring bone mineral density at the lumbar spine, hip trochanter, and femoral neck, according to a multicenter randomized study of almost 300 women with postmenopausal osteoporosis.