dihydrate crystal deposition disease--1975.
deposition disease (CPPD) is a condition that is characterized by the deposit of pyrophosphate crystals into tendons, ligaments, cartilage and synovium.
Bullough, "Tophaceous pseudogout (tumoral calcium pyrophosphate
dihydrate crystal deposition disease)," Human Pathology, vol.
In the 1960s, McCarty et al (12,13) discovered new crystals in the synovial fluid, which were calcium pyrophosphate
Two patients showed calcium pyrophosphate
crystals on polarized microscopy and two had no bacterial growth or crystals.
Haemochromatosis, rheumatoid metacarpophalangeal joints arthritis Prolonged stiffness after rest Inflammatory arthropathy including rheumatoid arthritis Rheumatoid factor positive Rheumatoid arthritis but low titre RF is often seen in the elderly Chondrocalcinosis on plain Calcium pyrophosphate
Psendogout: Similar to gout; however, the crystals in the synovial fluid are composed of calcium pyrophosphate
dihydrate and not uric acid.
In elderly patients, calcium pyrophosphate
dehydrate is a common finding in many fibrocartilages and hyaline articular cartilages of larger joints, tendons, and soft tissues.
dihydrate deposition in the intervertebral discs in a case of Wilson's disease.
Unlike in rheumatoid arthritis or secondary OA due to hemochromatosis, calcium pyrophosphate
disease, or trauma, there is no metacarpophalangeal joint or wrist involvement, stressed Dr.
However, calcium pyrophosphate
dehydrate deposition disease (CPPD) and rheumatoid arthritis are the differential diagnoses, which need to be evaluated both clinico-radiologically and with a histopathological examination.
Synovial fluid should be aspirated and analyzed if a palpable effusion is present, in order to confirm or exclude inflammatory disease and identifyurate and calcium pyrophosphate