calpain


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Related to calpain: cathepsin, calpastatin

calpain

[′kal‚pān]
(cell and molecular biology)
A calcium-dependent cysteine protease in the cytoplasm that is central to most processes in cell biology (plasma membrane-associated signaling events; cell proliferation, differentiation, activation, and communication; and programmed cell death). Its overactivation has been observed in muscular dystrophy, Alzheimer's disease, AIDS, cataract formation, multiple sclerosis, and arthritis.
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pp60src is an endogenous substrate for calpain in human blood platelets.
2+]-binding domain VI of rat calpain is a homodimer in solution: Hydrodynamic, crystallization and preliminary X-ray diffraction studies.
17) Proteins that compose the calcium network undergo oxidative modification through time, resulting in conformational changes, aggregation, and internalization from the plasma membrane and proteolytic degradation by the calcium-activated calpains and caspases.
Carcass characteristics, the calpain proteinase system, and aged tenderness of Angus and Brahman crossbred steers.
Independent of calpain, the researchers also found that host PKC played an important role in the loss of protein adducin from the host cytoskeleton, contributing greatly to its collapse.
Calpain 10 and development of diabetes mellitus in cystic fibrosis.
The expression of calcium signaling-related molecules showed significant increase in the frontal cortex of mice exposed to repeated blasts, including calpain 3 (1.
Vitex negundo attenuates calpain activation and cataractogenesis in selenite models.
Time course of diaphragm injury and calpain activity during resistive loading.
The calpain proteolytic enzyme system is responsible for the specific peptide bond cleavage which causes early postmortem tenderization [7].
This change is attributed to the increased expression of calpain, a calcium-activated protease.
Ann Scarborough Bull, Minerals Management Service Outlook On The Outer Continental Shelf For Offshore Energy 12:30-1:20 LUNCH BREAK Saturday, May 30, 2009 Location: Cecilia 202 Session: Research Trainiing Program Session II Chair: Martha Schwartz 117 1:40 MPP+ MEDIATES CALPAIN ACTIVATION IN PRIMARY NEURONS: A FLUORESCENT BASED ANALYSIS OF A PARKINSONIAN MODEL Alexa Aranjo, Mr.