capillary gel electrophoresis


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capillary gel electrophoresis

[¦kap·ə·ler·ē ¦jel i‚lek·trō·fə′rē·səs]
(analytical chemistry)
A form of capillary electrophoresis in which a polyacrylamide gel (or other polymeric material) is placed inside the capillary and separation is based on size and charge; often used to separate oligonucleotides and proteins.
References in periodicals archive ?
Guttman held appointments at Diversa Corporation (San Diego, CA) developing novel separation methods for bioindustrial scale carbohydrate analysis, at the Torrey Mesa Research Institute (La Jolla, CA) on microfluidics, Genetic BioSystems (San Diego, CA), on microgel electrophoresis and Beckman Coulter (Fullerton, CA) on capillary gel electrophoresis.
Here we report a quantitative PCR method, followed by separation by capillary gel electrophoresis of the fluorescently labeled amplified exons of hot spot regions of the dystrophin gene, which allowed us to detect ~99% patients (affected males and female carriers) with macrodeletions and 89% with macroduplications, and to identify small insertions or deletions in those regions.
High-resolution capillary gel electrophoresis of reducing oligosaccharides labeled with 1-aminopyrene-3,6,8-trisulfonate.
Because our method does not rely on restriction digestion, it has distinct advantages over other Apo E capillary gel electrophoresis methods (18-20).