Treatment with STW5 resulted in statistically significant protection against the reduction in responsiveness to carbachol
and serotonin in both the RS and NMS/RS models and to adrenaline in the NMS/RS model only.
Cumulative concentration-response curves were constructed for the smooth muscle stimulants carbachol
, KCl and serotonin on the basal contractility of the longitudinal muscle followed by cumulative concentration-response curves for the smooth muscle relaxant, adrenaline, on the same muscle strips pre-contracted with a submaximal dose of carbachol
(eliciting 60-70% of the response provoked by the maximal dose).
The contractile response of bladder strips to electrical field stimulation (EFS), carbachol
and potassium chloride (KCI) was determined for dif- ferent experimental groups.
Effect of mineral salts, carbachol
, and pilocarpine on nutrient digestibility and ruminal characteristics in cattle.
Using the M1 receptor antagonist pirenzepine (PIR), the M3 receptor antagonist 4-diphenyl-acetoxy-N-methyl-piperidine methiodide (4-DAMP), and the cholinergic agonist carbachol
, here we investigated the potential role of Ml and M3 mAChRs in mLTD induction and in increasing phosphorylated ERK levels in juvenile and adults rats.
infusion induced preconditioning with a marked depression of mean arterial blood pressure, heart rate and the total number of ventricular ectopic beats.
In another study on isolated tracheal preparations from ovalbumin-sensitized guinea pigs, vitamin E was found to reduce the contractile effects of ovalbumin and carbachol
The molecular mechanism of central analgesia induced by morphine or carbachol
and the L-argininenitric oxide-cGMP pathway.
A5 cells are silenced when REM sleep-like signs are elicited by pontine carbachol
is another miotic that is prescribed as drops and helps open the eye's drain and increase the rate of fluid flowing out of the eye.
stimulation of receptor coupled phospholipase C in the TRPC3 expressing cells increased TRPC3 surface expression, but was attenuated in cells where VAMP2 protein was degraded via tetanus toxin.
Two agonists, nicotine and carbachol
, offer near complete protection from alkylation, consistent with the expected results since the compounds are not hypothesized to be subtype-specific like mecamylamine and d-tubocurarine.