carboplatin


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carboplatin

[¦kär·bō′plat·ən]
(medicine)
A platinum coordination compound and anticancer agent used for advanced gynecologic malignancies, especially ovarian tumors, and for head and neck cancers and lung cancers.
References in periodicals archive ?
The investigators concluded that carboplatin drug monitoring should become routine practice for salvage regimens involving high-dose carboplatin.
Carboplatin was selected as the chemotherapy of choice as it is standard therapy in lung cancer.
Induction of Myelosuppression in Mice: Myelosuppression was induced in experimental mice by a single intraperitoneal injection of carboplatin (Pharmaplatin Inj.
As a pre-surgery treatment, the women were randomly assigned to receive either standard chemotherapy (a combination of paclitaxel, adriamycin, and cyclophosphamide), standard chemotherapy plus carboplatin, standard chemotherapy plus Avastin (a drug that blocks cancers from generating blood vessels), or standard chemotherapy plus both carboplatin and Avastin.
Conclusion: WBRT with carboplatin as radiation sensitizer is effective in palliation of patients with metastatic brain disease.
Using two cycle of carboplatin at a dose of 400mg/m2, Steiner & Colleagues reported relapse free survival in 106/108 patients at 60 months.
2] of docetaxel (Taxotere) intravenously for 1 hour on days 1 and 8, combined with carboplatin (AUC=6) IV on day 1, and repeated every 3 weeks for six cycles.
Those patients given carboplatin experienced fewer side effects and were able to get back to their normal lives quicker than the men on radiotherapy, the research found.
And the patients treated with carboplatin were also far less likely to develop cancer in their other testicle.
A study showing that a single dose of carboplatin chemotherapy is as effective and less toxic than radiation therapy in preventing recurrence after surgery for early-stage testicular cancer was presented at the American Society of Clinical Oncology annual meeting in Chicago, IL.
In men with surgically resected stage I seminoma, a single dose of carboplatin chemotherapy is as effective as 2 to 3 weeks of radiation therapy in preventing recurrence and is much less toxic, according to study findings presented at the American Society of Clinical Oncology annual meeting in Chicago.