In the cFGF-23 assay, antibodies detect 2 different epitopes in the carboxyl terminal
PROLOR's CTP technology is based on the naturally-occurring human carboxyl terminal
GP96 is the most abundant member of HSP90 in the endoplasmic reticulum (ER), contains an N-terminal signal sequence (70 amino acid), characteristic of the ER-targeted proteins and a carboxyl terminal
KDEL sequence (Lys-Asp-Glu-Leu), which is a retention/retrieval signal from the golgi to the ER.
PROLOR's CTP technology is based on a short amino acid sequence, the Carboxyl Terminal
Peptide that occurs naturally in humans.
HMG-CoA reductase is anchored in the membrane of the endoplasmic reticulum, and was long regarded as having seven transmembrane domains, with the active site located in a long carboxyl terminal
domain in the cytosol (9).
1] cells expressed an approximate 70-kDa band that was immunoreactive to a rabbit antibody directed to the intracellular carboxyl terminal
domain, unique to the P2X7 class of purinergic receptors (Figure 8).
Another important conserved feature identified through sequence analyses is the carboxyl terminal
domain of approximately 20 amino acids.
About PROLOR's CTP Technology PROLOR's CTP technology is based on the naturally-occurring human carboxyl terminal