carcinogen

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Related to carcinogenicity: mutagenicity, genotoxicity

carcinogen:

see cancercancer,
in medicine, common term for neoplasms, or tumors, that are malignant. Like benign tumors, malignant tumors do not respond to body mechanisms that limit cell growth.
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.

carcinogen

[kär′sin·ə·jən]
(medicine)
Any agent that incites development of a carcinoma or any other sort of malignancy.

carcinogen

Pathol any substance that produces cancer
References in periodicals archive ?
IARC assessments of carcinogenicity are based on, and necessarily limited to, scientific evidence available at the time of the review.
Alistair Currie, policy officer for People for Ethnic Treatment of Animals (Peta) said: "The current animal test for carcinogenicity is primitive, cruel and useless.
Ideally clinical trials should include carcinogenicity as a primary outcome measure, and longitudinal trials should examine carcinogenicity of classes of drugs and specific agents, in order to give clinicians a better sense of the risk/benefit equation when prescribing psychotropic agents, he recommended.
The veterans' case was largely thwarted in 1984 because of a lack of scientific evidence and Monsanto-sponsored studies which showed no increase in cancer among human subjects exposed to dioxin (studies that were later contradicted by EPA studies of the carcinogenicity of dioxin to humans).
The pre-clinical phase represents bench (in vitro) and then animal testing, including kinetics, toxicity and carcinogenicity.
This decision follows an announcement by the International Agency for Research on Cancer (IARC), whose experts reviewed EGBE and found inadequate evidence of carcinogenicity in humans and limited evidence of carcinogenicity in animals.
An interesting chapter in the book on cyclopenta[a]phenanthrenes attempts to relate the x-ray crystallographic data on molecular strain to carcinogenicity.
Hamburg's dismissal of standard carcinogenicity tests is bizarre.
As announced on August 1, 2011, the clinical holds placed on ARIKACE in NTM and Cystic Fibrosis (CF) patients with Pseudomonas lung infections were based on an initial review by FDA of the interim results of a long-term rat inhalation carcinogenicity study reported to the Agency by Insmed with ARIKACE.
12] The results of carcinogenicity assays have been equivocal, but the dye does appear to act as a tumor promoter.
739) report on the results of a workshop entitled "Genomics in Cancer Risk Assessment" that focused on the need to develop new approaches in carcinogenicity testing and human cancer risk assessment.
Each entry also includes recent references, including those on synthetic methods, major applications and safety, and toxicity data includes acute, aquatic, carcinogenicity, cytotoxicity, ecotoxicity, genotoxicity, hemotoxicity and other information as it is available.