Non-steroidal and steroidal anti-inflammatory drugs have serious side effects such as gastric erosions, ulcer formation, bleeding, hypersensitivity reactions, cardiovascular toxicity
, renal toxicity, and hepatotoxicity.
The TGA has received reports of adverse events after consumption of products containing both caffeine and oxedrine, including a report of teenagers experiencing serious cardiovascular toxicity
after using such a product in combination with alcohol and additional caffeine from an energy drink.
1136) assessed the impacts of load-related differences in DEE composition on models of inflammation, susceptibility to infection, and cardiovascular toxicity
of Selected Chemotherapy Agents Acute Coronary Heart Failure Hypertension Syndromes QTc Prolongation Anthracyclines Bevacizumab Fluorouracil Arsenic trioxide Trastuzumab Sorafenib Bevacizumab Depsipeptide Lapatinib Sunitinib Sorafenib Sunitinib Alemtuzumab VDAs * VDAs Dasatinib VDAs * Vascular disrupting agents Source: Dr.
The potential cardiovascular toxicity
of these dementia drugs may be under-appreciated by clinicians, Park-Wyllie adds.
The search for less toxic, long-acting LAs was prompted by fatalities associated with the cardiovascular toxicity
For more information on cardiovascular toxicity
associated with cancer treatment, refer to the full article by Viale and Yamamoto (2008).
The USA's Food and Drug Administration (FDA) banned the sale of products containing ephedrine alkaloids in 2004 because of associated cardiovascular toxicity
Toxicology reviews: Targeted management strategies for cardiovascular toxicity
from tricyclic antidepressant overdose: The pivotal role for alcalinisation and sodium loading.
Awareness of the risk of central nervous system and cardiovascular toxicity
and preparation for immediate commencement of resuscitation in the event of toxicity remain of paramount importance.
Celecoxib cannot currently be recommended for the prevention of sporadic adenomas until we understand more clearly its potential cardiovascular toxicity
and the mechanisms that underlie this," said Dr.
Although evidence of cardiovascular toxicity
is included in the pharmacologic literature regarding cocaine-derived anesthetics, it is our hope that with increased awareness regarding the occurrence of severe adverse cardiac events following the use of cocaine anesthetics, patients scheduled to undergo procedures involving this type of anesthesia will be screened more carefully to avoid negative outcomes.