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caspase

   Also found in: Dictionary/thesaurus, Acronyms, Wikipedia 0.01 sec.
caspase [′kas‚pās]
(cell and molecular biology)
Any of a family of intracellular proteins that mediate apoptosis.


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Cell cycle arrest or apoptosis involved caspase activation and altered Bcl-2 family member expression.
Ginkgo biloba extract; Renal ischemia/reperfusion; JNK; C-Jun; Fas/FasL; Caspase 3; Apoptosis Introduction Renal ischemia/reperfusion injury is the major cause of morbidity and mortality in diseases such as acute renal failure, renal transplantation, trauma, and major surgery.
In tests with primary T cells or Jurkat T leukemia cells, the extended presence of YopH led to apoptosis through a mitochondria-dependent pathway, as indicated by mitochondrial breakdown, caspase activation, DNA fragmentation, and annexin V binding.
 
 
 
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