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Catalase

   Also found in: Dictionary/thesaurus, Medical, Acronyms, Wikipedia 0.01 sec.
catalase [′kad·əl‚ās]
(biochemistry)
An enzyme that catalyzes the decomposition of hydrogen peroxide into molecular oxygen and water.

Catalase 

an enzyme of the hydroperoxidase group that catalyzes the oxidation-reduction reaction during which water and oxygen are formed from two molecules of hydrogen peroxide:

Catalase is obtained in crystalline form; its molecular mass is 250, 000. The enzyme is widely distributed in the cells of animals, plants, and microorganisms. It is a chromoprotein having an oxidized heme as a prosthetic (nonprotein) group. Since the specificity of catalase for a substrate-reducing agent is low, it can catalyze not only the decomposition of H202 but also the oxidation of the lower alcohols. The function of catalase is to destroythe toxic hydrogen peroxide that forms in the body during vari-ous oxidative processes.



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Studies conducted in the past have already shown that mice live longer when their genome is altered to carry a gene known as mitochondria-targeted catalase gene (MCAT).
Catalase removes the hydrogen peroxide and eliminates the antibacterial properties of most honeys, but manuka honey retains its antibacterial properties for reasons that are not clear.
Epidermal HA was endogenously labeled with 3H-glucosamine for 24 h, then chased for 24 h in the presence of superoxide dismutase (SOD) and catalase to reduce the concentration of ROS.
 
 
 
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