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cataplexy

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.04 sec.
cataplexy [′kad·ə‚plek·sē]
(medicine)
Sudden loss of muscle tone provoked by exaggerated emotion, such as excessive anger or laughter, often associated with a profound desire for sleep.
Prostration by the sudden onset of disease.
Hypnotic sleep.


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Cataplexy often occurs in response to strong emotions, such as surprise, anguish, or elation.
Even if clear-cut narcolepsy is present, per an incontrovertible history of cataplexy, overnight sleep laboratory monitoring usually still is warranted, due to the high prevalence of sleep apnea: even as an aggravating factor that could render treatment for narcolepsy less efficacious.
Xyrem has demonstrated an acceptable safety profile in narcoleptics with cataplexy when administered in nightly divided doses of 6 to 9 g with a recommended starting dose of 4.
 
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