Symptoms of narcolepsy include excessive daytime sleepiness (even dropping off to sleep at any time, whether it be watching TV or driving a car), cataplexy
(brief episodes of muscle weakness brought on by strong emotion), sleep paralysis (inability to move occurring at the moment of failing asleep), and hypnagogic hallucinations (dreamlike images that occur at sleep onset).
is almost uniquely associated with narcolepsy.
Other drugs may be prescribed for cataplexy
and sleep paralysis, but whatever the treatment, the patient must make considerable adjustments once this chronic disorder manifests itself.
Pharmaceutical company Flamel Technologies SA (Nasdaq:FLML ) reported on Friday the start of treatment of the first patient under its Rest-On Phase III clinical trial of FT218 for the treatment of excessive daytime sleepiness and cataplexy
in patients suffering from narcolepsy.
means if I have any emotional response to anything, such as laughing or crying, I can collapse.
It may sound funny, but cataplexy
is ruining my life.
She added: "Her cataplexy
means she can collapse at any time and there is so many dayto-day things that we take for granted that she can't do.
Results: Sleep latency and REM latency were longer in idiopathic hypersomnia group than in narcolepsy with and without cataplexy
Sadly Samantha also suffers from cataplexy
as part of the condition which means her muscles can collapse all of a sudden.
Narcolepsy is a rare, chronic nervous system disease that usually includes acute daytime drowsiness, episodic cataplexy
, sleep paralysis, hypnagogic hallucination and a disrupted sleep cycle.
It usually manifests itself as cataplexy
, in which wide-awake sufferers "flop" as if falling into a deep sleep, reports The Daily Express.
At a joint meeting, panelists generally agreed the data from clinical trials showed that sodium oxybate, which is approved for treating cataplexy
and daytime sleepiness associated with narcolepsy, was effective in treating fibromyalgia.