catenin


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catenin

[′kat·ə·nən]
(biochemistry)
Any of a family of 80-102-kilodalton proteins that are thought to have a major role in regulation of cell-to-cell adhesion, which is related to their interaction with E-cadherin and the actin cytoskeleton.
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p120 catenin regulates the actin cytoskeleton via Rho family GTPases.
The mice which were genetically-engineered to naturally produce large amounts of beta catenin developed skin tumours and.
Timing a lithium-induced rise in beta catenin with the arrival of these cells may optimize healing, he says.
These proteins include the functional component p120 catenin (p120.
Since the cadherins are known to associate intracellularly with catenins, we also examined whether [Beta]-catenin showed a similar pattern of nuclear reactivity in Merkel cell carcinomas.
1) The cytoplasmic domain of the cadherin molecule is complexed to a variety of molecules, including members of the catenin family, which link the cadherin to the actin cytoskeleton of the cell and may facilitate binding of the cadherin molecule to the cell surface.