DNA

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DNA:

see nucleic acidnucleic acid,
any of a group of organic substances found in the chromosomes of living cells and viruses that play a central role in the storage and replication of hereditary information and in the expression of this information through protein synthesis.
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DNA (deoxyribonucleic acid)

See GENETICS.

DNA

(biochemistry)

DNA

deoxyribonucleic acid; a nucleic acid that is the main constituent of the chromosomes of all organisms (except some viruses). The DNA molecule consists of two polynucleotide chains in the form of a double helix, containing phosphate and the sugar deoxyribose and linked by hydrogen bonds between the complementary bases adenine and thymine or cytosine and guanine. DNA is self-replicating, plays a central role in protein synthesis, and is responsible for the transmission of hereditary characteristics from parents to offspring

DNA

(1) See Windows DNA.

(2) (Digital Network Architecture) Introduced in 1978, it was Digital's umbrella term for its enterprise network architecture based on DECnet.
References in periodicals archive ?
25] Even so, an ideal endpoint of treatment would be to achieve viral eradication with sustained HBsAg loss, with/without seroconversion to anti-HBs antibodies, as HBsAg is a surrogate marker for transcriptionally active cccDNA.
Persistence of cccDNA during the natural history of chronic hepatitis B and decline during adefovir dipivoxil therapy.
Key points: Natural history and pathogenesis * Hepatitis B is a hepatotropic virus; liver injury occurs through immune-mediated killing of infected hepatocytes * Chronicity occurs rarely when the HBV infection is contracted in adulthood, but is common in neonates and young children * cccDNA is the transcriptional template for the viral mRNAs * Newly synthesised cytoplasmic viral capsids containing mature viral DNA are transported to the nucleus, thereby replenishing cccDNA * Cure is dependent on eradicating cccDNA * Understanding the natural history and phases of chronic infection is essential when making management decisions HBV = hepatitis B virus; cccDNA = covalently closed circular DNA; mRNA = messenger RNA.