strain

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Related to cell strain: cell line, secondary culture

strain:

see strength of materialsstrength of materials,
measurement in engineering of the capacity of metal, wood, concrete, and other materials to withstand stress and strain. Stress is the internal force exerted by one part of an elastic body upon the adjoining part, and strain is the deformation or change in
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.

Strain

 

a pure culture of a species of microorganism in which its morphological and physiological characteristics are studied.

Strains can be isolated from a variety of sources, for example, soil, water, or food, or they can be isolated from a single source at different times. Hence, the same species of bacterium, yeast, or microscopic fungus may have a great many strains, differing from one another in several characteristics, such as sensitivity to antibiotics and capacity to produce toxins and enzymes. Commercial strains of microorganisms developed as a result of selection and used in industry for the microbiological synthesis of proteins (including enzymes), antibiotics, vitamins, and organic acids are much more productive than wild strains.

strain

[strān]
(biology)
An intraspecific group of organisms that possess only one or a few distinctive traits and are maintained as an artificial breeding group.
(cell and molecular biology)
A population of cells derived either from a primary culture or from a cell line by the selection or cloning of cells having specific properties or markers.
(mechanics)
Change in length of an object in some direction per unit undistorted length in some direction, not necessarily the same; the nine possible strains form a second-rank tensor.

strain

A change in the form or shape of a body or material which is subjected to an external force.

strain

Any deformation or deflection in a body caused by stress. The strain is directly proportional to the stress, as a load is applied until the proportional limit is reached. Beyond that point, the strain may increase at a changing rate until the yield stress is reached, but the part will return to its original size and shape when the load is removed and the strain is zero. The body will be deformed if the yield stress is exceeded. The strain is recorded as the change of size over the original size.

strain

1
1. Music a theme, melody, or tune
2. a feeling of tension and tiredness resulting from overwork, worry, etc.; stress
3. a particular style or recurring theme in speech or writing
4. Physics the change in dimension of a body under load expressed as the ratio of the total deflection or change in dimension to the original unloaded dimension. It may be a ratio of lengths, areas, or volumes

strain

2
1. a group of organisms within a species or variety, distinguished by one or more minor characteristics
2. a variety of bacterium or fungus, esp one used for a culture
References in periodicals archive ?
Similar gene expression alterations in response to malathion exposure were found in all cell strains for nine genes: a) aldo-keto reductase 1 (AKR1C1), b)aldo-keto reductase 2 (AKR1C2), c) an estrogen-responsive gene (EBBIP), d) plasminogen activator (PLAT), e) centromere protein F (CPF), f) replication factor C (RFC3), g) thymidylate synthetase (TYMS), h) putative mitotic checkpoint kinase (BUB1), and i) a gene of unknown function (AI859865).
Highlighting the importance of interindividual variation, three of the four cell strains showed similar alterations in select genes.
For example, the four cell strains analyzed in this study have been genotyped for a variety of genes, particularly those involved in cell cycle control and xenobiotic metabolism.
Results of this experiment showed some similar expression patterns to those in the same cell strains exposed to benzo[a]pyrene (Keshava et al.
He said he had objected to the Tokyo District Court's ruling in July declaring the cell strains to be collateral for the loans and the court seizure of the cell strains later that month.
No legal provisions exist to ban the purchase or sale of cell strains, and research institutions affiliated with universities sell strains for about 17,000 to 29,000 yen per ampoule to other research institutions.
The Ministry of Education, Culture, Sports, Science and Technology set guidelines this spring requiring researchers to obtain the consent of individuals whose genes are used in studies, but did not set legal provisions that ban transactions of cell strains for research purposes.
The NIID launched an investigation on Friday into the incident in which Okumura took the human cell strains out of the institute.
Under NIID guidelines, researchers are required to file applications for research using human cell strains, which are then considered based on the institute's ethics regulations.