strain

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Related to cell strain: cell line, secondary culture

strain:

see strength of materialsstrength of materials,
measurement in engineering of the capacity of metal, wood, concrete, and other materials to withstand stress and strain. Stress is the internal force exerted by one part of an elastic body upon the adjoining part, and strain is the deformation or change in
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.

Strain

 

a pure culture of a species of microorganism in which its morphological and physiological characteristics are studied.

Strains can be isolated from a variety of sources, for example, soil, water, or food, or they can be isolated from a single source at different times. Hence, the same species of bacterium, yeast, or microscopic fungus may have a great many strains, differing from one another in several characteristics, such as sensitivity to antibiotics and capacity to produce toxins and enzymes. Commercial strains of microorganisms developed as a result of selection and used in industry for the microbiological synthesis of proteins (including enzymes), antibiotics, vitamins, and organic acids are much more productive than wild strains.

strain

[strān]
(biology)
An intraspecific group of organisms that possess only one or a few distinctive traits and are maintained as an artificial breeding group.
(cell and molecular biology)
A population of cells derived either from a primary culture or from a cell line by the selection or cloning of cells having specific properties or markers.
(mechanics)
Change in length of an object in some direction per unit undistorted length in some direction, not necessarily the same; the nine possible strains form a second-rank tensor.

strain

A change in the form or shape of a body or material which is subjected to an external force.

strain

Any deformation or deflection in a body caused by stress. The strain is directly proportional to the stress, as a load is applied until the proportional limit is reached. Beyond that point, the strain may increase at a changing rate until the yield stress is reached, but the part will return to its original size and shape when the load is removed and the strain is zero. The body will be deformed if the yield stress is exceeded. The strain is recorded as the change of size over the original size.

strain

1
1. Music a theme, melody, or tune
2. a feeling of tension and tiredness resulting from overwork, worry, etc.; stress
3. a particular style or recurring theme in speech or writing
4. Physics the change in dimension of a body under load expressed as the ratio of the total deflection or change in dimension to the original unloaded dimension. It may be a ratio of lengths, areas, or volumes

strain

2
1. a group of organisms within a species or variety, distinguished by one or more minor characteristics
2. a variety of bacterium or fungus, esp one used for a culture
References in periodicals archive ?
Genes are listed for each cell strain (1-4) with columns showing SLR for microarray analysis with the associated p-value along with the RT-PCR result for each time point.
According to a report in the Mainichi Shimbun, a major Japanese daily, Okumura offered the cell strains as collateral for loans he borrowed from a Tokyo businessman.
These technologies allow us immediate entry into a new segment of the drug discovery market with cell strains already under evaluation with several key customers," commented Dave Eansor, President, Bioproducts.
Human cell strains belonging to the head of a researchers' association were auctioned Friday at a Tokyo hospital, marking the first auction of human cells in Japan.
The significance of this patent issuance is that it recognizes Transkaryotic's contribution in demonstrating, for the first time, stable transfection and gene targeting in normal cells as well as methods suitable for developing cell strains for use in gene therapy," commented Douglas Treco, PhD, Transkaryotic's senior vice president, research and development.
In another study presented at the meeting, Geron scientists demonstrated that hESCs could be grown using serum-free medium conditioned by placental fibroblasts or other human cell strains.