cell-mediated immunity


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cell-mediated immunity

[¦sel ¦mē·dē‚ād·əd i′myü·nəd·ē]
(immunology)
Immune responses produced by the activities of T cells rather than by immunoglobulins.
References in periodicals archive ?
Cell-mediated immunity was considered positive when the net increase was >0.
Most patients with CMC have a selective defect of cell-mediated immunity.
When HIV infection progresses to AIDS, Langerhans cells that carry HIV are depleted from the skin and substantially decrease in number, completely compromising cell-mediated immunity.
Both antibody levels and pertussis-specific cell-mediated immunity levels were higher in subjects who received the booster than in controls.
Mantoux testing elicits a delayed hypersensitivity reaction to a previously sensitized antigen (a T-lymphocyte function), and it is generally accepted as a valid in vivo indicator of a patient's level of cell-mediated immunity.
To test this hypothesis we considered that the adverse immunotoxic effects of PRN exposure on cell-mediated immunity might be observed in one or more of three parameters: a) presentation of peptide antigen to CTLs by antigen-presenting cells (APCs), b) proliferation and differentiation of CTLs, and/or c) functional lytic response of activated CTL effectors.
Recurrent viral and fungal infections, failure to thrive, persistent diarrhea, and Pneumocystis carinii infections are associated with defective cell-mediated immunity.
Cell-mediated immunity does the job with a white blood cell called the killer, or cytotoxic, T cell.
AIDS was simply defined as "a disease, at least moderately predictive of a defect in cell-mediated immunity, occurring in a person with no known cause for diminished resistance to that disease.
1] Human T-lymphotropic virus 1-infected patients with adult T-cell leukemia/lymphoma, however, are immunocompromised and specifically have defects of cell-mediated immunity.
This mobilization is called cell-mediated immunity.
The initial stages of humoral immunity are very similar to those of cell-mediated immunity.

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