The female to male ratio for all age groups and all variants is close to 2:1 (9) the lesions are typically asymptomatic, but growth of the types with central lesion
results in cortical expansion, as in the case reported here.
Physician assistant respondents frequently selected sputum cytology as their first diagnostic test, despite their estimate of its low sensitivity for central lesions
Endobronchial ultrasound can be used in central lesions
located near the distal trachea, mainstem bronchus, or proximal lower lobes, particularly if the clinician uses a central endobronchial ultrasound probe.
Also diagnostic yield from central lesions
is better than peripheral if adequate material is obtained.
sup] One hundred and eight patients (114 tumors) received the following SABR schedules: 48 Gy in 4 fractions or 54-60 Gy in 3 fractions for peripheral lesions and 50-60 Gy in 8-10 fractions for central lesions
Because NF1 often has central lesions
and NF2 can occasionally have peripheral manifestations, the terms central and peripheral have been discarded.
They typically develop in the shoulder, pelvic girdles, and proximal long bones, and they typically occur as central lesions
within the intramedullary cavity.