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centromere

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.05 sec.

centromere

Structure in a chromosome that holds together the two chromatids. It is the point of attachment to the structure that pulls the chromatids to opposite ends of the cell during cell division (see mitosis). During the middle stage of mitosis, the centromere duplicates and the chromatid pair separates, each chromatid becoming a separate chromosome. Thus, when the cell divides, both daughter cells have complete sets of chromosomes.



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Decreased expression of six RNA species was seen at various time points in all cell strains analyzed: plasminogen activator (PLAT), centromere protein F (CPF), replication factor C (RFC3), thymidylate synthetase (TYMS), a putative mitotic checkpoint kinase (BUB1), and a gene of unknown function (GenBank accession no.
``They occasionally talk about cellular structure and when they say centromere, I know what it looks like because I remember seeing them on slides here,'' he said.
Any DNA that doesn't have a centromere, you don't want, even if it came from you," he says.
 
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