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centromere |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.04 sec. |
centromereStructure in a chromosome that holds together the two chromatids. It is the point of attachment to the structure that pulls the chromatids to opposite ends of the cell during cell division (see mitosis). During the middle stage of mitosis, the centromere duplicates and the chromatid pair separates, each chromatid becoming a separate chromosome. Thus, when the cell divides, both daughter cells have complete sets of chromosomes. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Thereafter, we accomplished the hybridization using protein-nucleic acid probes (provided by DakoCytomation, Glostrup, Denmark) targeted against the centromeric region of the X chromosome (rhodamine-labeled) and the q-arm of the Y chromosome (labeled with fluorescein isothiocyanate). The Nature Methods article describes a whole-genome fractionation technique that can identify centromeric DNA in genomes, and suggests these techniques could be extended to crops and mammals. Serum antinuclear antibodies specific to Sm, double-stranded DNA, SSM/Ro, SSB/La, histone, RNP, Scl-70, Jo-1, and centromeric antigens were analyzed using Hep-2 nucleus antigens with the BINDAZYME ANA (antinuclear antibody) EIA Kit (The Binding Site, Birmingham, UK). |
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