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centromere
(redirected from centromeric)

    Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.04 sec.

centromere

Structure in a chromosome that holds together the two chromatids. It is the point of attachment to the structure that pulls the chromatids to opposite ends of the cell during cell division (see mitosis). During the middle stage of mitosis, the centromere duplicates and the chromatid pair separates, each chromatid becoming a separate chromosome. Thus, when the cell divides, both daughter cells have complete sets of chromosomes.

centromere [′sen·trə‚mir]
(cell and molecular biology)
A specialized chromomere to which the spindle fibers are attached during mitosis. Also known as kinetochore; kinomere; primary constriction.


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Thereafter, we accomplished the hybridization using protein-nucleic acid probes (provided by DakoCytomation, Glostrup, Denmark) targeted against the centromeric region of the X chromosome (rhodamine-labeled) and the q-arm of the Y chromosome (labeled with fluorescein isothiocyanate).
Impact of PCB and p,p'-DDE contaminants on human sperm Y:X chromosome ... by Giwercman, Aleksander / Environmental Health Perspectives
The Nature Methods article describes a whole-genome fractionation technique that can identify centromeric DNA in genomes, and suggests these techniques could be extended to crops and mammals.
Nature Methods Publishes Breakthrough by Chromatin Co-Founder for ... by Business Wire
Serum antinuclear antibodies specific to Sm, double-stranded DNA, SSM/Ro, SSB/La, histone, RNP, Scl-70, Jo-1, and centromeric antigens were analyzed using Hep-2 nucleus antigens with the BINDAZYME ANA (antinuclear antibody) EIA Kit (The Binding Site, Birmingham, UK).
Associations between plasma DDE levels and immunologic measures in ... by Germolec, Dori R. / Environmental Health Perspectives
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