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Cf |
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Cf, symbol for the element californium californium (kăl`ĭfôr'nēəm) ..... Click the link for more information. . cystic fibrosis (CF)or mucoviscidosisInherited metabolic disorder characterized by production of thick, sticky mucus. It is recessive (see recessiveness) and the most common inherited disorder (about 1 per 2,000 live births) in those of European ancestry. Concentrated mucous secretions in the lungs plug the bronchi, making breathing difficult, promoting infections, and producing chronic cough, recurrent pneumonia, and progressive loss of lung function, the usual cause of death. The secretions interfere with digestive enzymes and block nutrient absorption. Abnormally salty sweat is the basis for diagnosis of cystic fibrosis. Treatment includes enzyme supplements, a diet high in calories, protein, and fat, vigorous physical therapy, and antibiotics. Persons with cystic fibrosis once seldom survived beyond childhood; now more than half reach adulthood, though males are usually sterile. CFSee CompactFlash. Cf (chemistry)
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This is the first step in an approach scientists hope will one day correct the underlying genetic defect causing CF. Using a new technique called gene therapy, physicians at the National Heart, Lung, and Blood Institute in Bethesda, MD, hope to go beyond just treating the symptoms of CF. Copernicus' unique, non-viral nanoparticle formulation is intended to deliver a normal copy of the CF gene to the affected lung cells of CF patients, and may provide a therapy that treats the root cause of CF. |
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