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Related to chancroid: granuloma inguinale, syphilis


see sexually transmitted diseasesexually transmitted disease
(STD) or venereal disease,
term for infections acquired mainly through sexual contact. Five diseases were traditionally known as venereal diseases: gonorrhea, syphilis, and the less common granuloma inguinale, lymphogranuloma venereum, and
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(soft chancre; also called venereal ulcer in Russian), an infectious disease in man, caused by the streptobacillus Hemophilus ducreyi, or Ducrey’s bacillus (described in the late 1880’s and early 1890’s by the Russian O. V. Petersen, the Italian A. Ducrey, and the German P. Unna) and transmitted mainly through sexual intercourse.

The causative agent of chancroid is found in the discharge from the chancre; under a microscope it looks like a short rod with rounded ends and a slender middle. Two to five days after infection, a pustule forms over a bright red edematous spot at the site of entry of the infection; the pustule opens three or four days later and becomes a small painful ulcer with ragged edges, undermined by a purulent deposit and with a soft base encircled by a red edematous rim. The purulent discharge from such ulcers reaches the surrounding tissues and gives rise to numerous new ulcerations, which become scarred after a month or two. When the streptobacilli penetrate the regional lymphatic nodes, the latter become enlarged (bubo formation); they coalesce and fuse with the skin, soften, and open to form ulcers. The process is accompanied by local pain, high temperature, and general malaise.

Treatment includes the use of antibacterial agents and immersion of the affected area in a warm manganese bath. (SeeVENEREAL DISEASES for a description of preventive measures.)


Mnogotomnoe rukovodstvo po dermato-venerologii, vol. 1. Moscow, 1959. Pages 448–57.


A lesion of the genitalia, usually of venereal origin, caused by Hemophilus ducreyi. Also known as soft chancre.
References in periodicals archive ?
Table 1 Aetiological Assays Used to Detect RTIs Infection Detection Assay Nature of Sample Candidiasis Culture-Gram Stain Vaginal smear Bacterial Culture-Gram Stain Vaginal smear Vaginosis Trichomoniasis Culture Posterior vaginal smear Chlamydia Direct Fluorescent Endo-cervical vaginal Antibody (DFA) smear Endo-cervical vaginal Gonorrhoea Culture smear Syphilis Rapid Plasma Serum Reagin (RPR) Genital Herpes Culture Cells from lesions Smear from the base Chancroid Culture of the ulcer, pus removed HPV Cellular Endo/ecto-cervix Morphology cells Other (1) Culture Vaginal/cervical smear Source: Nayab (2005a).
Chancroid lesions may be difficult to distinguish from ulcers caused by genital herpes or syphilis.
One reason why uncircumcised men could be at higher risk of contracting HIV and passing it to others is that they are at higher risk of developing ulcerative STDs, particularly chancroid.
Infected women have a higher incidence than do HIV negative women of a number of gynecological diseases, including syphilis, herpes, chancroid, PID and genital warts caused by Human Papilloma Virus (HPV).
Until the early 1980s, the scope of recognized STDs included only five traditional infections: syphilis, gonorrhea, chancroid, lymphogranuloma venereum and granuloma inguinale.
com/research/zdhdlm/future_horizons) has announced the addition of the "Future Horizons in the Global Chancroid Diagnostic Market: US, Europe, Japan - Test Volume, Sales Forecasts and Supplier Shares by Country" report to their offering.
com/research/9cktwh/2016_global) has announced the addition of the "2016 Global Sexually-Transmitted Disease (STD) Testing Market: Chancroid, Chlamydia, Gonorrhea, Herpes, HPV, Syphilis--France, Germany, Italy, Japan, Spain, UK, US" report to their offering.
PCR has been shown to be highly sensitive and specific for diagnosing chancroid (6).
Chancroid in HIV-infected individuals may be resistant to standard regimens.
Neutropenia restores virulence to an attenuated Cu,Zn superoxide dismutase-deicient Haemophilus ducreyi strain in the swine model chancroid.
Circumcision is thought to have some protective effect on the spread of diseases such as penile carcinoma, urinary tract infections, and ulcerative sexually transmitted diseases, especially chancroid and syphilis.
Systematic reviews show that circumcised men are at significantly lower risk of syphilis and chancroid.