channel protein

channel protein

[′chan·el ‚prō‚tēn]
(cell and molecular biology)
Protein forming an aqueous pore spanning the lipid bilayer of the cell membrane which when open allows certain solutes to traverse the membrane.
References in periodicals archive ?
Ketamine is an antagonist of the N-methyl-D-aspartate (NMDA) glutamate receptor and an ion channel protein.
The deletion, concerned with an in-frame deletion of 5 amino acid residues in a highly evolutionarily conserved region within the cytoplasmic loop domain of the gap junction channel protein connexin 50 (Cx50), was in full cosegregation with the cataract phenotypes in the family but not found in 1100 control exomes.
com)-- Scientific experiments examining what happens to the faulty channel protein that causes cystic fibrosis during inflammation have yielded unexpected and exciting results.
Aquaporins in Saccharomyces: characterization of a second functional water channel protein.
Secondary structure and assembly mechanism of an oligomeric channel protein.
The precise control of this movement relies on the direct physical interaction between a calcium channel protein ryanodine receptor (RYR), and a calcium-sensing protein called calmodulin.
1 channel protein is able to shorten action potential.
Using high throughput DNA sequencing methods they were able to pin down the underlying cause of the condition to mutations in the AQP5 gene, which encodes a water channel protein known as aquaporin 5.
The CALHM1 channel protein, which spans a taste bud cell's outer membrane to allow ions and molecules in and out, releases ATP to make a neural taste connection.
1 channel protein levels were increased significantly after 18 h of hypoxia, while the protein level of [alpha]-actin was unchanged (Figure 2).
Although none of this progress addresses the damaged cystic fibrosis transmembrane conductance regulator (CFTR) ion channel protein, these general approaches extended the median survival of patients with cystic fibrosis from around 10 years to nearly 40 years.
Based upon its abnormal distribution in SS salivary glands, a potential role of the water channel protein aquaporin-5 (AQP-5) in the pathogenesis of SS was proposed.