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chelate |
Also found in: Dictionary/thesaurus, Medical, Hutchinson | 0.06 sec. |
chelateAny of a class of coordination or complex compounds consisting of a central atom of a metal (usually a transition element) attached to a large molecule (ligand). Any ligand that can bind to the metal at two or more points to form a ring structure, more stable than a nonchelated compound of the same general chemical formula, is a chelating agent. The process of binding to the metal is called chelation. Chelating agents such as EDTA salts are used in medicine to remove toxic metals (e.g., lead, cadmium) from the body. Others are used in analysis as indicators and in industry to extract metals. The iron-binding porphyrin group in hemoglobin, the magnesium-binding porphyrin in chlorophyll, and the cobalt-binding porphyrin in vitamin B12 are natural chelators. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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Neurobehavioral function and tibial and chelatable lead levels in 543 former organolead workers. A 4-hr urine collection after oral administration of 10 mg/kg dimercaptosuccinic acid (DMSA) was also obtained to measure DMSA chelatable lead and creatinine clearance (787 participants completed this collection). The estimated concentration of iron bound to the LMW ligands (the so-called chelatable iron) is 1-10 [micro]M in rodent and human cells (Petrat et al. |
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