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chelate |
Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson | 0.02 sec. |
chelateAny of a class of coordination or complex compounds consisting of a central atom of a metal (usually a transition element) attached to a large molecule (ligand). Any ligand that can bind to the metal at two or more points to form a ring structure, more stable than a nonchelated compound of the same general chemical formula, is a chelating agent. The process of binding to the metal is called chelation. Chelating agents such as EDTA salts are used in medicine to remove toxic metals (e.g., lead, cadmium) from the body. Others are used in analysis as indicators and in industry to extract metals. The iron-binding porphyrin group in hemoglobin, the magnesium-binding porphyrin in chlorophyll, and the cobalt-binding porphyrin in vitamin B12 are natural chelators. chelate [′kē‚lāt] (invertebrate zoology) Pertaining to an appendage with a pincerlike organ or claw. (organic chemistry) A molecular structure in which a heterocyclic ring can be formed by the unshared electrons of neighboring atoms. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| It chemically captures, or chelates, excess iron but must be given intravenously or by injection. The effect of succimer treatment to significantly increase the excretion of Pb in the urine is consistent with the action of this drug to form aqueous soluble chelates with Pb (12), as well as with a large body of clinical and laboratory evidence showing increased urinary excretion of Pb with treatment (1,17,25,26). Generally, chelates improve the absorption of minerals by about five or ten percent, but they cost five times as much. |
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