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chelate
(redirected from chelator)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.03 sec.

chelate

Any of a class of coordination or complex compounds consisting of a central atom of a metal (usually a transition element) attached to a large molecule (ligand). Any ligand that can bind to the metal at two or more points to form a ring structure, more stable than a nonchelated compound of the same general chemical formula, is a chelating agent. The process of binding to the metal is called chelation. Chelating agents such as EDTA salts are used in medicine to remove toxic metals (e.g., lead, cadmium) from the body. Others are used in analysis as indicators and in industry to extract metals. The iron-binding porphyrin group in hemoglobin, the magnesium-binding porphyrin in chlorophyll, and the cobalt-binding porphyrin in vitamin B12 are natural chelators.


chelate [′kē‚lāt]
(invertebrate zoology)
Pertaining to an appendage with a pincerlike organ or claw.
(organic chemistry)
A molecular structure in which a heterocyclic ring can be formed by the unshared electrons of neighboring atoms.


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In all cases, several cycles of chelator administration given over a period of months are required to produce an adequate and durable reduction of Pb in blood.
Our final step is to use transdermal DMPS, a chelator that can be applied to the skin.
We want chelators that are specific for our [radioactive] metals of interest" but that don't bind to others, such as calcium, which is a major ingredient of concrete and marble, says Mark E.
 
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