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chelate |
Also found in: Dictionary/thesaurus, Medical, Hutchinson | 0.04 sec. |
chelateAny of a class of coordination or complex compounds consisting of a central atom of a metal (usually a transition element) attached to a large molecule (ligand). Any ligand that can bind to the metal at two or more points to form a ring structure, more stable than a nonchelated compound of the same general chemical formula, is a chelating agent. The process of binding to the metal is called chelation. Chelating agents such as EDTA salts are used in medicine to remove toxic metals (e.g., lead, cadmium) from the body. Others are used in analysis as indicators and in industry to extract metals. The iron-binding porphyrin group in hemoglobin, the magnesium-binding porphyrin in chlorophyll, and the cobalt-binding porphyrin in vitamin B12 are natural chelators. chelate [′kē‚lāt] (invertebrate zoology) Pertaining to an appendage with a pincerlike organ or claw. (organic chemistry) A molecular structure in which a heterocyclic ring can be formed by the unshared electrons of neighboring atoms. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| An uneven effectiveness of water-soluble chelators at removing Pb from particular organs is another problem with existing protocols for the treatment of Pb intoxication, with bone (Castellino and Aloj 1964; Cory-Slechta 1988; Gerhardsson et al. Starting children on the program younger appears to lead to faster and better results, and approaching the chelation process with a combination of chelators, supplementation, dietary intervention, and regular laboratory testing minimizes the chances of side effects. We want chelators that are specific for our [radioactive] metals of interest" but that don't bind to others, such as calcium, which is a major ingredient of concrete and marble, says Mark E. |
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