chelerythrine


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chelerythrine

[‚kel·ə′rī‚thrēn]
(organic chemistry)
C21H17O4H A poisonous, crystalline alkaloid, slightly soluble in alcohol; it is derived from the seeds of the herb celandine (Chelidonium majus) and has narcotic properties.
References in periodicals archive ?
chelidonine, sanguinarine, chelerythrine, protopine and berberine.
U0126 was used at 20 [micro]M and chelerythrine was at 5 [micro]g/ml.
When chelerythrine (a PKC inhibitor, 5 [micro]g/ml) was added 30 min before the treatment with lesatropane, it could somewhat reduce ERK1/2 activation (Figure 5B) and the neuroprotective effect of lesatropane by 62.
We also show that TGF-[beta]-induced ROS production and TGF-[beta]1 expression require PKC activity as indicated by the inhibition using chelerythrine.
7A illustrates that the inhibition of PKC activity by chelerythrine (10 [micro]M) prevented TGF-[beta]-induced ROS production in [C.
Chelerythrine, a specific PKC inhibitor, blocks acquisition but not consolidation and retrieval of conditioned taste aversion in rat.
Protein kinase C inhibitor chelerythrine disrupts memory formation in chicks.
The content of the alkaloids chelidonine, protopine, coptisine, berberine, sanguinarine and chelerythrine was quantified by RPHPLC-DAD.
In vitro and in vivo activity of protein kinase C inhibitor growth delay in vivo chelerythrine chloride induces tumor cell toxicity and growth delay in vivo.
DNA adduct formation from quaternary benzolclphenanthridine alkaloids sanguinarine and chelerythrine as revealed by the P-32-postlabeling technique.
Quaternary benzo[c]phenanthridine alkaloids sanguinarine and chelerythrine have been used in folk medicine for their wide range of useful properties.
Chelerythrine (CHE, a PKC inhibitor), 5-hydroxydecanoate (5HD, a selective blocker of mito [K.