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chemical carcinogenesis |
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chemical carcinogenesis [¦kem·i·kəl ‚kär·sə·nə′gen·ə·səs] (medicine) The chemical-induced cancerous transformation of normal cells via a multistep process in which the genetic code of the cells is altered and then the altered cells are promoted to form tumors. How to thank TFD for its existence? Tell a friend about us, add a link to this page, add the site to iGoogle, or visit webmaster's page for free fun content. |
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| Mice deficient in COX-2 develop 75% fewer tumors than their wild type littermates when subjected to a 9,10-dimethylbenz[a]anthracene/12-O-tetradecanoylphorbol-13-acetate two-stage chemical carcinogenesis protocol (Tiano et al. We know these compounds can probably cause cancer in humans," says Elizabeth Snyderwine, Chief of the Chemical Carcinogenesis Section at the National Cancer Institute (NCI) in Bethesda, Maryland. He chaired a number of federal committees and task forces, including the development and implementation of the Technology Transfer Act of 1986 and the White House Task Force on Chemical Carcinogenesis. |
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