Genetically altered mice are being evaluated as possible replacements for, or adjuncts to, conventional rodents for bioassays of chemical carcinogenesis
(Donehower et al.
The role of glutathione and glutathione transferases in chemical carcinogenesis
And it's worth repeating that resveratrol can inhibit all three stages of chemical carcinogenesis
, an unusual phenomenon and highly significant in the treatment of cancer.
They present the core concepts, skills, and methods to perform risk assessments, including the fundamentals of cancer biology, chemical carcinogenesis
, hormesis, and experimental evidence of thresholds for genotoxic carcinogens; guidelines and regulations for in vitro and in vivo testing; and evaluation of toxicological data and its relevance to hazard evaluation and cancer risk estimation.
Inhibitory effects of Nigella sativa and saffron (Crocus sativus) on chemical carcinogenesis
Koepke also spent 10 years at the National Cancer Institute investigating the mechanisms of chemical carcinogenesis
com/research/f66cb9/cancer_risk_assess) has announced the addition of John Wiley and Sons Ltd's new book "Cancer Risk Assessment: Chemical Carcinogenesis
, Hazard Evaluation, and Risk Quantification" to their offering.
Topics include the comparative pathology of mammary gland cancers in domestic and wild animals, neoplasia in nonhuman primates, mouse models of breast cancer, comparison of genetically engineered mouse mammary cancer models and human breast cancer by expression profiling, genetically engineered rat models, chemical carcinogenesis
of rat and mouse mammary glands, comparative genetics and genomes of rat models, toxicogenomic analyses of genetic susceptibility to mammary gland carcinogenesis in rodents and the applications for breast cancer, and the relationship between comparative medicine, "one medicine," and genomic pathology.
In various models of chemical carcinogenesis
, carcinogen induces ODC activity and inhibitors of ODC suppress cancer development.
A multihit, multistage model of chemical carcinogenesis
Next come chapters on tissue context as a determinant of the tumor-suppressive or oncogenic function of certain genes, cancer stem cells, pharmacogenomics and determination of therapeutic efficacy, chemical carcinogenesis
, hormones and cancer, and viral oncogenesis.
The role of glutathione and glutathione S-transferase in chemical carcinogenesis