While most adenomas are composed of chief cells
, a small percentage may be oxyphilic (>90% oxyphils) and rare "water-clear" adenomas have also been described.
Primary chief cell
hyperplasia of the parathyroid glands: a new entity in the surgery of hyperparathyroidism.
Furthermore, in the untreated control group, the gastric mucosa is intact and no observed ulceration seen with foveolar, parietal, and chief cells
in normal conditions (Figure 3a).
The chief cells
and the oxyntic cells can be made out in the gastric glands.
Photomicrograph showing chief cells
with pale eosinophilic cytoplasm and round to oval nuclei surrounded by sustentacular cells (hematoxylin-eosin, original magnification X20).
Present study revealed that oxyphil cells were less numerous than chief cells
, placed either at periphery of gland adjacent to capsule or in the centre of gland.
In the new report, Mills, graduate student Greg Sibbel and Hans Clevers, MD, PhD, a geneticist at Utrecht Medical Centre, identified markers that show a small number of chief cells
become stem cells even in the absence of serious injury.
The normal paraganglia consists of nests of chief cells
(type1) and sustentacular cells (type 2).
In heavy drinkers, however the liver's chief cells
-- called parenchymal cells -- can suffer such a severe damage that scar tissue forms, resulting in a condition known as cirrhosis.
Histologically, pernicious anemia is characterized by gastric mucosal atrophy, selective loss of parietal and chief cells
from the gastric mucosa, and submucosal lymphocytic infiltrate.