chief cell

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chief cell

[¦chēf ′sel]
(histology)
A parenchymal, secretory cell of the parathyroid gland.
A cell in the lumen of the gastric fundic glands.
References in periodicals archive ?
Normally, an intact muscularis externa, submucosa, and gastric mucosa will reflect the presence of chief cells found just above the submucosa occupying one-fourth of the entire gastric mucosa.
Fragmentation of gastric mucosa, dissolution of cellular outlines and collapsed chief cells are few, visible characteristics.
Photomicrograph showing chief cells, which are focally immunoreactive for tyrosine hydroxylase (original magnification X20).
C(1984) (26) that oxyphil cells may represent a non-secretary stage in life cycle of chief cells.
Based on effective TPEF of cellular nicotinamide adenine dinucleotide phosphate and flavin adenine dinucleotide and the lack of TPEF of mucin and cellular nuclei, MPM can easily identify different types of cells, such as squamous epithelial cells, goblet cells, foveolar gastric mucous neck cells, parietal cells, and chief cells.
Mills, graduate student Greg Sibbel and Hans Clevers, a geneticist at Utrecht Medical Center, identified markers that show a small number of chief cells become stem cells even in the absence of serious injury.
While most adenomas are composed of chief cells, a small percentage may be oxyphilic (>90% oxyphils) and rare "water-clear" adenomas have also been described.
Paragangliomas are composed of two cell types: chief cells and sustentacular cells.
26,28) These are composed of chief cells and sustentacular cells in a nesting or zellballen pattern.
Histologically, these tumors appear highly vascular and are composed of clusters (Zellballen, which is German for "cell balls") of chief cells supported by sustentacular cells and small blood vessels.

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