chitin


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chitin

(kīt`ən), main constituent of the shells of arthropods. Chitin, a polysaccharide (see carbohydratecarbohydrate,
any member of a large class of chemical compounds that includes sugars, starches, cellulose, and related compounds. These compounds are produced naturally by green plants from carbon dioxide and water (see photosynthesis).
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) analogous in chemical structure to cellulosecellulose,
chief constituent of the cell walls of plants. Chemically, it is a carbohydrate that is a high molecular weight polysaccharide. Raw cotton is composed of 91% pure cellulose; other important natural sources are flax, hemp, jute, straw, and wood.
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, consists of units of a glucose derivative (N-acetyl-d-glucosamine) joined to form a long, unbranched chain. Like cellulose, chitin contributes strength and protection to the organism. In arthropods the chitinous shell, or exoskeleton, covers the surface of the body, does not grow, and is periodically cast off (molted). After the old shell is shed, a new, larger shell is secreted by the epidermis, providing room for future growth. The chitin is rigid except between some body segments and joints where it is thin and allows movement of adjacent parts. Chitin is also found in the cell walls of some fungi.

Chitin

A polysaccharide found abundantly in nature. Chitin forms the basis of the hard shells of crustaceans, such as the crab, lobster, and shrimp. The exoskeleton of insects is also chitinous, and the cell walls of certain fungi contain this substance.

Chitin is a long, unbranched molecule consisting entirely of N-acetyl- d -glucosamine units linked by β-1,4 bonds (see illustration). It may be thought of as cellulose in which the hydroxyl groups on the second carbon are replaced with NHCOCH3 groups. Chitin is considered to be synthesized in nature by an enzyme which is capable of effecting a glycosyl transfer of the N-acetyl- d -glucosamine from uridinediphosphate-N-acetyl- d -glucosamine to a preformed chitodextrin acceptor, forming the polysaccharide. This stepwise enzymic transfer results in the production of the long chain of β-N-acetyl- d -glucosamine units, which is insoluble chitin. See Polysaccharide

β- N -acetyl- D -glucosamine unit of chitinenlarge picture
β-N-acetyl- D -glucosamine unit of chitin

Chitin

 

a natural polysaccharide; the basic component of the exoskeleton, or cuticula, of arthropods and certain other invertebrates; also found in the cell walls of fungi and bacteria. Chitin performs protective and supportive functions by ensuring cell rigidity. The term “chitin” was proposed by the French scientists A. Audier, who in 1823 investigated the hard outer covering of insects.

Chitin consists of residues of N-acetyl glucosamine linked by β1,4 glycoside bonds. Its molecular weight may be as high as 260,000. It is insoluble in water, dilute acids, alkalies, and organic solvents, including alcohol; it is soluble in concentrated solutions of salts (thiocyanate of lithium and calcium), and it breaks down in concentrated solutions of mineral acids when heated. As found in nature, chitin is always associated with proteins; it is analogous to the cellulose of plants in its structure, physical and chemical properties, and biological functions.

The biosynthesis of chitin in an organism is effected by the transfer of a donor residue of N-acetylglucosamine from uridine-diphosphate-N-acetylglucosamine to chitodextrin acceptors—with the participation of the enzymatic glycosyltransferase system that is associated with the intracellular membranes. The biological decomposition of chitin down to free N-acetylglucosamine is effected by chitinase, an enzyme found in a number of bacteria and among the digestive enzymes of soil amoebas and certain snails and earthworms, as well as in crustaceans during the molting period. When an organism dies, chitin and the productions of its decomposition are converted to humin-like compounds in the soil and sea sediments, thus promoting the accumulation of nitrogen in the soil.

N. D. GABRIELIAN

chitin

[′kīt·ən]
(biochemistry)
A white or colorless amorphous polysaccharide that forms a base for the hard outer integuments of crustaceans, insects, and other invertebrates.

chitin

a polysaccharide that is the principal component of the exoskeletons of arthropods and of the bodies of fungi
References in periodicals archive ?
Crystallinity, which varies according to the source of chitin and can also be altered during processing of the biopolymer, controls the accessibility to its sorption sites and its diffusion properties.
Chitin and chitosan have many excellent properties including biocompatibility, biodegradability, nontoxicity, and absorption, and thus they can be widely used in a variety of areas such as biomedical applications, agriculture, water treatment, and cosmetics.
Chitin metabolism in insects: structure, function and regulation of chitin synthases and chitinases.
Digestion of chitin by the labial glands of Acromyrmex octospinosus Reich (Hymenoptera: Formicidae).
Despite the fact the functionality of chitin derivatives spans across various applications, ranging from dietary' supplements to healthcare, these biopolymers remain an underutilized resource.
Recognized by human and environmental enzymes such as lisozyme, chitinase, acetyl-glucosaminidase and lipases, chitin is easily transformed to oligomers and/ or reduced to glucose and glutamic acid.
7) Family-18 chitinases hydrolyze chitin and have been identified in bacteria, fungi, insects, plants, viruses and protozoan parasites.
Statistical analysis: Data of DM and NDF disappearance and chitin content of medium were analysed as repeated measurement using the General Linear Model (GLM) procedure of SAS (1990).
An impressively international group of contributors from fields that include chemistry, applied bioscience, biosurface technology, biotechnology, and applied marine biotechnology report on the sources, production, physical and chemical aspects, and the applications of chitin and chitosan derivatives for industry, agriculture, and biotechnology.
They found that the cell wall chitin and fatty acids in mycorrhizal fungi have distinct spectral signatures, absorbing infrared light at different wavelengths than standard chitin, fatty acids, and nonmycorrhizal roots.
Many other hydrogels used in medicine today are based on biological materials such as chitin, a structural component found in the cell walls of certain fungi, the beaks of squid and the shells of lobsters and crabs.
Since our RNAi is focused on chitin synthesis, the dsRNA that is delivered into the mosquito larvae can basically block the production of chitin," Zhu said.