chlorpromazine


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chlorpromazine

(klōrpräm`əzēn'), one of a group of tranquilizing drugs called phenothiazinesphenothiazine
, any one of a class of drugs used to control mental disorders. Phenothiazines, along with other antipsychotic, or neuroleptic, drugs are used for such disorders as schizophrenia, paranoia, mania, psychosis resulting from mental deficiency, some forms of senility,
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 that are useful in halting psychotic episodes. Chlorpromazine, sold under the trade name Thorazine, is often used to reduce the severe anxietyanxiety,
anticipatory tension or vague dread persisting in the absence of a specific threat. In contrast to fear, which is a realistic reaction to actual danger, anxiety is generally related to an unconscious threat.
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 and agitation and the overactivity of some forms of schizophreniaschizophrenia
, group of severe mental disorders characterized by reality distortions resulting in unusual thought patterns and behaviors. Because there is often little or no logical relationship between the thoughts and feelings of a person with schizophrenia, the disorder has
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.

chlorpromazine

[klȯr′prō·mə‚zēn]
(pharmacology)
C17H19ClN2S A gray-white, crystalline compound used as a sedative and in preventing or relieving nausea and vomiting.
References in periodicals archive ?
In order to standardize different medications' doses for the comparison, they were converted to chlorpromazine equivalent for all participants in the present study.
Less frequently, cases related to chlorpromazine and rarely to other phenothiazines are reported.
Deniker and others embarked upon clinical trials using four daily injections of chlorpromazine in doses that were considered high at the time--75 to 150 mg per day.
Many of these compounds' benefits for treating mental disorders were discovered serendipitously Drug class Prototype History of use compound Mood stabilize Lithium Used to treat gout in the 1800s, its effect on mood was found a century later Antipsychotic Chlorpromazine Synthesized in 1950 and initially tested as an anesthetic Antidepressant Imipramine A failed schizophrenia drug, imipramine turned out to lift depression Sedative Chlordiazepoxide First tested in lions and other zoo animals SOURCE: S.
19) Among the TAP, haloperidol carries least risk of weight gain, while chlorpromazine carries highest.
Oral ketamine/midazolam is superior to intramuscular meperidine, promethazine,and chlorpromazine for pediatric cardiac catheterization.
The other most commonly prescribed drugs were (in order) risperidone, haloperidol, olanzapine, chlorpromazine, trifluoperazine, and quetiapine.
Potentiating effect of Mentha arvensis and chlorpromazine in the resistance to aminoglycosides of methicillin--resistant Staphylococcus aureus.
I find that the administration of morphine, diamorphine and chlorpromazine by Dr Martin was not clinically justified and more than minimally or trivially contributed to and accelerated his death," Mr Tweddle said.
Claiming, according to an SKF psychiatric journal advertisement, that "mental patients are notorious drug evaders," the company created a liquid chlorpromazine that they could not escape.
The 87-year-old, of Luetrout Lane, Solihull, had been prescribed a drug called Chlorpromazine in a bid to control his over-active diaphragm.
The development of 'atypical' antipsychotics was stimulated by a landmark study in 1988 that showed clozapine to be superior in efficacy to chlorpromazine in schizophrenic patients resistant to high doses of haloperidol.