cholecystokinin


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Related to cholecystokinin: enterogastrone, secretin

cholecystokinin

[‚kō·lə‚sis·tə′kī·nən]
(biochemistry)
A hormone produced by the mucosa of the upper intestine which stimulates contraction of the gallbladder.
References in periodicals archive ?
1998) A disrupted cholecystokinin A receptor gene induces diabetes in obese rats synergistically with ODB1 gene.
Cortical changes in cholecystokinin mRNA are related to spontaneous pain behaviors following excitotoxic spinal cord injury in the rat.
Cholecystokinin (CCK) is the regulatory peptide hormone found primarily in the gastro-intestinal tract that works as a neurotransmitter throughout the nervous system.
The effect of sildenafil on gallbladder motility is presumably carried out two ways: first, increase of intracellular cGMP by the inhibition of type 5 phosphodiesterase and relaxation of smooth muscle cells at postprandial gallbladder contraction phase (direct effect); and second, decrease of cholecystokinin release resulting from inhibition of gastroduodenal motility (indirect effect).
Eating fat-rich foods causes cells in the small intestine to produce a hormone called cholecystokinin, or CCK, which can even protect against potentially lethal bacteria.
Cholecystokinin, dopamine D2 and N-methyl-D-aspartate binding sites in the nucleus of the solitary tract of the rat: Possible relationship to ingestive behavior.
The study focused on the hormone called cholecystokinin (CCK), which is in the small intestines.
We know that marathon runners have increased levels of cholecystokinin, a chemical messenger found in the intestines that triggers the contraction of the gallbladder.
In addition, synthesis of the neuropeptide cholecystokinin (CCK) increases following nerve injury.
These values are lower than expected for the inactivation of solubilized proteins and than found for brain cholecystokinin receptors and solubilized muscarinic receptors [15, 16], but in good agreement with the activation energy of the inactivation of muscarinic receptors in rat cortical membranes, in which case the determining role of surrounding lipids has been proposed [15].