acetylcholine receptor

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Related to cholinergic receptor: adrenergic receptor, Nicotinic receptor

acetylcholine receptor

[ə‚sed·əl ′kō‚lēn ri‚sep·tər]
(cell and molecular biology)
A receptor in the membranes of certain cell structures, such as synapses or the neuromuscular junction, to which the transmitter substance acetylcholine binds. Nicotinic acetylcholine receptors are gated ion channels that open in response to acetylcholine, leading to an increase in membrane conductance; muscarinic acetylcholine receptors are G-protein-linked receptors inducing membrane ion channel changes or intracellular processes such as smooth muscle contraction.
References in periodicals archive ?
Keywords: Catharanthus roseus roots Catharanthine Ajmalicine Serpentine Acetylcholinesterase Cholinergic Receptors
That receptor, which contains the nicotinic a-7 cholinergic receptor subunit, is necessary to inhibit the release of TNF and other pro-inflammatory cytokines.
The first is independent of cholinergic receptor expression and influences cell replication through effects on intracellular messengers (9,12,14).
The inhibition of these enzymes increases the availability of Ach, which in turn can stimulate cholinergic receptors producing both nicotinic and muscarinic effects in the organism such as muscle contractions and secretions in many glands (5).
QUEBEC CITY, Quebec, June 18, 2014 /PRNewswire/ -- Asmacure Ltee, a clinical-stage biopharmaceutical company focused on the development of novel, proprietary compounds that target cholinergic receptors for the treatment of pulmonary diseases, today announced top-line results from a combined Phase 1 and 2a trial evaluating its lead compound, ASM-024, in moderate asthma patients.
HET] mice have reduced ACh transmission by central cholinergic neurons (22), compensatory mechanisms, such as supersensitivity of cholinergic receptors, could account for the normal sleep-wake physiology.
Ipratropium bromide, which is used frequently as a bronchodilator in patients with bron-chospasm, is a direct antagonist of muscarinic cholinergic receptors.
Expression and distribution of cholinergic receptors in the human urothelium.
to polybrominated diphenyl ether (PBDE 153) disrupts spontaneous behaviour, impairs learning and memory, and decreases hippocampal cholinergic receptors in adult mice.
Nondepolarizing agents cause muscle paralysis by affecting the postsynaptic cholinergic receptors at the neuromuscular junction.
Haley and his colleagues reasoned that if low-level satin or pesticides had damaged Gulf Was Veterans' brains, a likely target of the damage would be cholinergic receptors on cells in certain brain structures.
Nicotinic cholinergic receptors have been demonstrated on keratinocytes, which may control keratinocyte adhesion and upward migration in the epidermis," Dr.