Chondrosarcoma

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chondrosarcoma

[¦kän·drō·sär′kō·mə]
(medicine)
A malignant tumor of cartilage.

Chondrosarcoma

 

a malignant tumor of cartilage tissue, sometimes accompanied by mucous degeneration; a type of sarcoma. Chondrosarcomas most often occur in males. They develop mostly on the inferior metaphysis of the femur, the pelvic bones, and the ribs. The course is slow (several years); pain appears when the tumor has attained considerable size. Metastasis is mainly to the lungs and lymph nodes. Treatment involves surgery (amputation, resection) combined with the administration of antineoplastic agents.

References in periodicals archive ?
A 58-year-old male with multiple enchondromas experienced malignant degeneration of one into a chondrosarcoma of the distal femur.
Histopathologically, chondrosarcomas are divided into two types: conventional and variant.
Malignancies included osteosarcoma, fibrosarcoma, chondrosarcoma, and malignant fibrous histiocytoma.
Histological examination (Fig 2) showed the mass to be a chondrosarcoma (grade 1).
Unlike chondrosarcoma of bone, there are no differentiated cartilage cells with distinct lacunae seen.
18-fluoro-2-deoxy-D-glucose (F18 FDG) uptake has been shown to be proportional to tumor grade, with high standardized uptake values predictive of highergrade chondrosarcomas.
With characteristic determination Ann tracked down Professor Michael Gleeson, a head and neck surgeon who had operated on 13 patients with Cranial Chondrosarcoma.
This randomized, double-blind trial is designed to compare the safety and efficacy of IPI-926 to matching placebo in patients with metastatic or locally advanced, inoperable chondrosarcoma.
On MRI, low grade, differentiated chondrosarcomas will appear bright on T2 imaging, with more homogeneous signal than that of higher-grade lesions.
It represents only 2% to 10% of all chondrosarcomas (2-7) and has a frequency of 0.
8) The majority are chondrosarcomas, however, osteosarcomas and malignant fibrous histiocytomas have been reported.
Background & Purpose: Chondrosarcomas compose 25% of malignant bone tumors and are the third most common type of primary bone tumor.