While the distantly related Lymphocytic choriomeningitis
virus is generally harmless in healthy humans, the Lujo virus demonstrates an unprecedented high case fatality rate of 80% and unusual degree of pathogenicity.
virus infection in organ transplant recipients--Massachusetts, Rhode Island, 2005.
Molecular testing results were negative for rickettsiae, filoviruses (Marburgviruses and Ebolaviruses), selected bunyaviruses (Rift Valley fever virus, Crimean Congo hemorrhagic fever virus), arenaviruses (Lassa, Lujo, and lymphocytic choriomeningitis
viruses), and several arbo-viruses (yellow fever, dengue, O'nyong-nyong, chikungunya, and Zika viruses).
These case studies originated from a case in May 2005 in which two kidney transplant recipients developed the donor transmitted Lymphocytic Choriomeningitis
Virus (LCMV) that is typically found in rodents.
At least 6 organ transplant recipients in the US have died after being infected with lymphocytic choriomeningitis
virus (LCMV), by a virus rarely found in humans transmitted by rodents such as hamsters and mice.
virus (LCMV), a rodentborne arenavirus, is a rare, zoonotic cause of aseptic meningitis in Europe and North America.
The recent cases occurred in New England and Wisconsin and involved pet hamsters infected with Lymphocytic choriomeningitis
(LCM), a rodent-borne viral infectious disease.
virus (LCMV), a rodentborne arenavirus, causes inapparent infection in mice but can cause febrile illness, aseptic meningitis, encephalitis, and severe birth defects in humans (www.
When mice, which T cells express TK were infected with the lymphocytic choriomeningitis
virus, administration of GCV resulted in an efficient, but transient, control of the immunopathological immune response.
CMV quantitative PCR and testing for lymphocytic choriomeningitis
IgM and IgG were requested, but not obtained.
More recently, infectious disease pathology has been instrumental in the investigation of a multistate outbreak of fungal meningitis associated with epidural injection of steroid preparations and in the identification of several organ transplant--associated infections, such as lymphocytic choriomeningitis
virus, Balamuthia disease, and rabies.
Her rat brings to mind rodent-borne pathogens, including a novel hantavirus and lymphocytic choriomeningitis
virus, and her dogs bring to mind reports of the resurgence of rabies virus.