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chorion
(redirected from chorionic)

   Also found in: Dictionary/thesaurus, Medical, Wikipedia, Hutchinson 0.02 sec.
chorion [′kȯr·ē·än]
(embryology)
The outermost of the extraembryonic membranes of amniotes, enclosing the embryo and all of its other membranes.

Chorion

The outermost of the several extraembryonic membranes in amniotes (reptiles, birds, and mammals) enclosing the embryo and all of its other membranes. The chorion, or serosa, is composed of an outer layer of ectodermal cells and an inner layer of mesodermal cells, collectively the somatopleure. Both layers are continuous with the corresponding tissue of the embryo. The chorion arises in conjunction with the amnion, another membrane that forms the outer limb of the somatopleure which folds up over the embryo in reptiles, birds, and some mammals. The chorion is separated from the amnion and yolk sac by a fluid-filled space, the extraembryonic coelom, or body cavity. In those mammals in which the amnion forms by a process of cavitation in a mass of cells, instead of by folding, the chorion forms directly from the trophoblastic capsule, the extraembryonic ectoderm, which becomes gradually underlain by extraembryonic mesoderm.

In reptiles and birds the chorion fuses with another extraembryonic membrane, the allantois, to form the chorioallantois, which lies directly below the shell membranes. An extensive system of blood vessels develops in the mesoderm of this compound membrane which serves as the primary respiratory and excretory organ for gaseous interchanges. In all mammals above the marsupials, the chorion develops special fingerlike processes (chorionic villi) extending outward from its surface. To a varying degree in different species of mammals, the villous regions of the chorion come into more or less intimate contact with the uterine mucosa, or uterine lining, of the mother, thereby forming the various placental types. See Allantois, Amniota, Fetal membrane, Germ layers



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Both amniocentesis and another procedure called chorionic villus sampling, in which doctors pluck bits of the placenta, isolate fetal cells that can reveal many genetic problems in an unborn baby with near certainty.
Chorionic villus sampling, to detect genetic abnormalities in the embryo or fetus in the first trimester.
A reduction in circulating levels of estrogens and insulin-like growth factor 1 (IGF-1) and/or elevated levels of progesterone, androgens, human chorionic gonadotrophin, IGF-1 binding proteins 1 and 3, cortisol, and insulin have been associated with reduced risk.
 
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