chromophobe


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Related to chromophobe: chromophobe adenoma, chromophobe renal cell carcinoma

chromophobe

[′krō·mə‚fōb]
(biology)
Not readily absorbing a stain.
References in periodicals archive ?
Clear cell, papillary and chromophobe renal cell carcinoma in patients younger than 20 years old: A clinicopathologic study with follow-up.
Based on biomarker analysis, we speculate that 5-fluorouracil, gemcitabine, or temozolomide might be active in advanced chromophobe RCC because of the lack of expression of TS, RRM1, and MGMT, respectively," observed Philip Abbosh, M.
At that time histology of the left kidney revealed a 165 mm chromophobe renal cell carcinoma which did not breach the renal capsule but did demonstrate vascular space invasion and renal sinus invasion.
By applying EZH2 immunohistochemical staining using TMA, Wagener et al (63) studied 520 RCCs including 423 CRCCs, 45 PRCCs, 23 chromophobe RCCs, 3 collecting duct carcinomas, and 17 unclassified carcinomas.
1,4) Renal mass biopsy is the most reliable diagnostic modality, but can be complicated by histopathological similarities between oncocytoma and eosinophilic variants of chromophobe renal cell carcinoma (RCC).
Chromophobe renal cell carcinoma accounts for approximately 5% of all renal neoplasms and is a distinct subtype of renal cell carcinoma.
IMP3 is also an independent prognostic biomarker for patients with localized papillary and chromophobe RCC.
The Rosetta Kidney Cancer Test (TM) accurately classifies the four most common kidney tumors: clear cell renal cell carcinoma (RCC), papillary RCC, chromophobe RCC and oncocytoma.
Pathological examination has revealed renal cell carcinoma in 19 cases (13 with clear cell, 5 with papillary cell, 1 with chromophobe cell) and angiomyolipoma in 1 case.
The study demonstrates the ability of microRNAs to accurately identify four histological types of renal tumors, namely clear cell, papillary, and chromophobe renal cell carcinoma, as well as oncocytoma, a benign tumor.
Also, loss of INI1 is helpful to differentiate MRT from other primary renal neoplasms (15) with rhabdoid differentiation including clear cell, transitional cell, papillary, chromophobe, and collecting duct carcinomas (16-18).
The tumors were renal cell carcinoma, clear cell type (254), papillary type (62), or chromophobe type (29); oncocytoma (30); urothelial cell carcinoma (33); angiomyolipoma (14); and miscellaneous (27).