chromosome painting


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chromosome painting

[′krō·mə‚sōm ‚pānt·iŋ]
(genetics)
Rendering a specific chromosome or chromosome segment distinguishable by deoxyribonucleic acid hybridization with a pool of many fluorescence-labeled DNA fragments derived from the full length of a chromosome or segment.
References in periodicals archive ?
Comparative chromosome painting discloses homologous segments in distantly related mammals.
He is credited with the development and implementation of many important technologies, including high-speed sorting; flow karyotyping; the first chromosome painting probes; development of interphase fluorescent in situ hybridization (FISH); and the first demonstration using FISH showing ERBB2 amplification and BCR-ABL translocation, both of which are critically important to current patient management.
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