chromosome walking


Also found in: Medical.

chromosome walking

[′krō·mə‚sōm ‚wȯk·iŋ]
(genetics)
Sequential isolation of overlapping molecular clones in order to span large intervals on the chromosome.
References in periodicals archive ?
05 cM) of the molecular map around the gene will be attained with the screening of a 2000 individual segregating population with AFLP markers Besides, a BAC genomic library and a cosmid library will be creened in order to identify clones positive for the markers linked to Ry to start the chromosome walking in the region and to find a BAC clone which contain molecular markers placed at both sides of the gene
TKT's system for chromosome walking represents a major advance in efficiency over state-of-the-art technology and is focused on the isolation of genes associated with common diseases.
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