Hepatitis E is usually an acute, self-limiting hepatitis without progression to a chronic carrier
state, just like hepatitis A.
Subjects were categorized into 2 groups according to their clinical and serologic profiles, specifically, an HBV natural convalescent group and an HBV chronic carrier
Hepatitis B virus (HBV) infection causes a spectrum of acute and chronic liver disease ranging from inactive chronic carrier
status to progressive chronic hepatitis, culminating in end-stage cirrhosis and liver cancer.
The danger associated with being a chronic carrier
of any hepatitis virus is the increased risk of developing cirrhosis and hepatocellular carcinoma.
Another line of evidence comes from a study looking at bone marrow transplantation from hepatitis B virus immune subjects to chronic carrier
To have discovered a chronic carrier
state in the gall bladder of an animal model, suggesting a potential source of food contamination, is important," said senior author Christopher Contag, PhD, assistant professor of pediatrics and of microbiology and immunology.
As occurs with hepatitis B but not with hepatitis A, a chronic carrier
state can develop after hepatitis C infection.
If the patient in our study was a chronic carrier
, she should have had manifestations of acute West Nile encephalitis immediately following the first course of combination chemotherapy, which was much more immunosuppressive than cyclophosphamide alone.
Conclusion : A chronic carrier
rate less than 2 per cent suggests that India is a country with low endemicity (5).
In the future, antigen detection will guide patient management decisions; therefore, the possibility of a human chronic carrier
state warrants study.
Surveillance should also be considered for these chronic carriers
of hepatitis B even without the presence of cirrhosis: Asian males over 40, Asian females over 50, African American men, and any carrier with a family history of HCC.
Those who fail to clear the infection after six months may become chronic carriers
, able to pass on the infection.