chronic myeloid leukemia


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chronic myeloid leukemia

[′krän·ik ′mī·ə‚loid lü′kem·ē·ə]
(medicine)
A form of leukemia in which immature granulocytes are predominant and the life expectancy is 1-20 years or more.
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Ranakkel and colleagues presents a myasthenia gravis (without thymoma) patient who developed chronic myeloid leukemia 68 months after receiving a thymectomy and steroids.
Dasatinib induces significant hematologic and cytogenetic responses in patients with imatinib-resistant or -intolerant chronic myeloid leukemia in accelerated phase.
Chronic myeloid leukemia makes up about 15 per cent of all cases of leukemia among adults.
Extended results of the phase III International Randomized Study of Interferon Versus STI571 (IRIS) trial showed 89% overall survival in 553 newly diagnosed Philadelphia chromosome-positive chronic myeloid leukemia (CML) patients treated with imatinib, with less than 5% of the deaths related to the CML.
Characteristics and outcome of chronic myeloid leukemia patients with F317L BCR-ABL kinase domain mutation after therapy with tyrosine kinase inhibitors.
Assessment of BCR-ABL1 transcript levels at 3 months is the only requirement for predicting outcome for patients with chronic myeloid leukemia treated with tyrosine kinase inhibitors.
The drug, a dual SRC/ABL kinase inhibitor known as BMS-354825, was administered to 36 patients with chronic myeloid leukemia between November 2003 and November 2004 at the Jonsson Comprehensive Cancer Center at the University of California, Los Angeles, and the M.
In a retrospective, single-center study, patients with first chronic phase chronic myeloid leukemia (CML) who underwent peripheral blood stem cell transplantation (PBSCT) fared better than those treated with bone marrow transplantation (BMT) from HLA-compatible unrelated donors.
Efficacy and Safety of Ponatinib in Patients with Accelerated Phase or Blast Phase Chronic Myeloid Leukemia (AP-CML or BP-CML) or Philadelphia Chromosome-Positive Acute Lymphoblastic Leukemia (Ph+ ALL): 12-Month Follow-up of the PACE Trial
and Europe with chronic myeloid leukemia and Philadelphia chromosome-positive acute lymphoblastic leukemia.

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